muscle and skeleton Flashcards

(43 cards)

1
Q

sessile

A

non moving

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2
Q

non-sessile

A

freely moving

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3
Q

molecular motors

A

proteins capable of converting energy in ATP into movement

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4
Q

kinesins

A

move along microtubules by consuming ATP
found in all eukaryotic cells

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5
Q

dyneins

A

transport cellular cargo/organelles
cilia and flagella

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6
Q

dyneins

A

transport cellular cargo/organelles
cilia and flagella

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7
Q

myosin

A

head - binds actin, consumes ATP, force transduction
neck - lever
tail - regulation, interacts with proteins
found in all eukaryotic cells

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8
Q

myocytes

A

muscle cells needed to coalesce into larger structures

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9
Q

myofibrils

A

larger fibers constructed from myocytes
connected to other structures (when they move, other tissues move)

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10
Q

muscle evolution in sponges

A

contract body sections without muscle cells
require - molecular motors, contractile fibers, connection to cell cytoskeleton

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11
Q

contractile apparatus

A

filaments and molecular motors
triggered by calcium (calmodium)
used by sponges

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12
Q

muscle evolution properties

A

generates force through shortening (tension)
under conscious and unconscious control
dependent on the action of molecular motors

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13
Q

amoeboid

A

change cell shape
crawling motion done by protozoans, slime molds
actin/myosin motors

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14
Q

cilia and flagella

A

asymmetrical // symmetrical
one // many
axoneme

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15
Q

functional characteristics

A

contraction - fibers shorten, generate force and pull on bones, slide past each other
excitability - respond to stimulus, CNS, hormones, physical
extensibility - stretch past original length
elasticity - recoils after stretch

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16
Q

striated muscle anatomy

A

long cells innervated by neurons (conscious control)
usually associated with skeletons as anchorage points

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17
Q

smooth muscle anatomy

A

individual small cells
same molecular motors as striated
much higher efficiency
activated by stretch

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18
Q

sarcomere

A

contractile unit of striated muscle within muscle fibers
attached end to end, z-disk to z-disk, in series

19
Q

sarcoplasmic reticulum

A

ER
ca2+ storage

20
Q

terminal cisternae

A

ca2+ sequestering

21
Q

transverse tubules

A

cell membrane invaginations

22
Q

actin filament

A

thin filament, overlaps myosin filament
attached to z-disk

23
Q

nebulin

A

scaffolding protein

24
Q

tropomyosin

A

barrier to interaction between myosin and actin
keeps muscle from contracting

25
troponin
binds calcium to tropomyosin C - binds ca2+ I - binds actin, preventing molecular interaction with myosin T - binds tropomyosin
26
z disk
site of actin attachment, also attached to cell cytoskeleton
27
I band
region with only actin
28
A band
region of actin/myosin overlap
29
H zone
region with only myosin
30
M line
site of attachment of myosin
31
length-tension curve
relationship between muscle length (or sarcomere length) and tension development ideal overlap = maximum number of crossbridges formed
32
invertebrate striated muscle
thick filament is 2-3x thicker, 2-5x longer paramyosin attached to myosin twitchin protein allows muscle to maintain resistance to stretch in absence of cross bridge asynchronous
33
smooth muscle activation
ca2+ influx into cell ca2+ binds to calmodulin myosin light chain kinase is activated myosin light chain is phosphorylated cross bridge forms, tension develops
34
mechanochemical coupling
only power half of the action of the muscle found in thorax and associated muscles
35
mechanical oscillator
thorax, stretch rubber band can use smaller set of wings to generate more lift with less muscle
36
resilin
elastic protein found in fleas striated muscle
37
skeleton
rigid weight bearing, composite with strength and flexibility
38
biomechanical advantage of skeletons
levers around a joint
39
joints
move without friction
40
endoskeleton
mineralized tissue (collagen), hydroxyapatite crystals
41
exoskeleton
limits growth carry the weight
42
hydrostatic skeleton
flexible chamber filled with water
43
buoyancy
upward force exerted by a fluid that opposed the weight of an immersed object