Muscle Physiology - Winden Flashcards Preview

DMD 5246- Integrated Systems/ Disease and Wellness 1 > Muscle Physiology - Winden > Flashcards

Flashcards in Muscle Physiology - Winden Deck (33)
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1

What are the functions of skeletal muscle?

Provides movement, generates heat, stores nutrient reserves, supports soft tissues, maintain posture and body position, guards entrances and exits

2

What are the three different types of CT associated with skeletal muscle?

epimysium
perimysium
endomysium

3

What does epimysium cover?

Covers the entire muscle
Connects to the deep fascia

4

What does the perimysium cover?

Covers the fascicle

5

What does the endomysium cover?

Covers the muscle fiber

6

Describe the difference between a tendon and a aponeurosis

Tendon is the extensions of all the CT from the muscle that is attached to the bone

Aponeurosis is a sheet of the CT extension (ie. on the head)

7

What are characteristics of skeletal muscle?

Voluntary
Striated
Multinucleated
Long and can be large
Develop from the fusion of myoblasts

8

Name from smallest to largest the units of skeletal muscle

Myofilament, myofibril, myofiber, fascicle, muscle

9

What is the triad consist of?

Two terminal cisternae and T-tubule

10

What is distinct about the A band?

Length of the thick filament (dark)

11

What is distinct about the I band?

Length between the ends of each thick filament (light)

12

What is distinct about the M line?

Middle of the sarcomere and the center of the A band

13

What is distinct about the H band?

The area of ONLY thick filaments

14

What is distinct about the Z lines?

The center of the I band

15

What is nebulin?

In the thin filament
Holds the two strands of F-actin together

16

What is tropomysosin?

Two strands that block the active sites on the globular actin

17

What is troponin?

Moves tropomyosin when binding with Ca

18

What is titin?

Recoils myosin after contraction

19

What are the components of myosin?

Head and Neck
Has active sites for both actin and ATP

20

What is the sliding filament theory

Thin filaments move toward the M line
Width of the A band stays the same
Z lines move closer together

21

What does contraction duration depend on?

Duration of neural stimulus
Amount of Ca
Avaliability of ATP

22

What occurs with rigor mortis?

After a body has died, there is no ATP but abundant Ca
Cannot rest muscles

23

Twitches have 3 phases:
What are they?

latent- Ca release
contraction- Ca binding
relaxation - Ca decrease

24

What is Treppe?

Repeated stimulation right after relaxation

25

What is Wave?

Stimuli arrives before relaxation has completed

26

What is Tetanus and the two types?

Repeated stimuli with little or no relaxation

Incomplete- little relaxation
Complete- no relaxation

27

What does skeletal muscle tension depend on?

internal and external tension
total number of muscle fibers

28

What is a motor unit?

All the muscle fibers that are controlled by a single neuron

29

What would you do to get a smooth contraction?

Recruitment

30

What is muscle tone?

The firmness and tension of the muscle fiber at rest