Musculoskeletal system Flashcards

(41 cards)

1
Q

What makes up the Musculoskeletal system?

A
  • Bones
  • Mucles
  • Joints, cartilage, tendons
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2
Q

Name some common problems (pathologies) of bone?

A
  • Fractures
  • Osteoporosis
  • Arthritis
  • Osteomyelitis
  • Tumours
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3
Q

What are the stages of fracture healing?

A
  • Haematome + granulation tissue
  • Cartalidge callus
  • Bony Callus and certilaginous remnants
  • Remodelling
  • Repair tissue reached max’ girth 2-3 weeks
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4
Q

What factors can limit fracture healing?

A
  • Bone not aligned
  • Are not immobilised
  • Fracture site contains dead bone
  • Infection
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5
Q

What condition is characterised by decreased bone mass and density and can lead to fractures?

A

Osteoporosis

Very common in the uk (3mil)

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6
Q

Name some characteristics of osteoporosis?

A
  • Decreased bone mass + density
  • Imbalance between bone resorption and bone production
  • Inadequate peak bone mass
  • Excess bone reabsorbs
  • Inadequate bone production
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7
Q

What factors can put someone at risk of Osteoporosis?

A
  • Hormonal infulences such as lack of oestrogen (oestrogen causes reduced bone resorption and increases bone formation)
  • Lack of Vit D and Calcium
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8
Q

Characteristics of Arthritis???

A
  • Pain
  • Swelling / inflammation
  • Warmth over joint (erythema)
  • Restricted movement
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9
Q

Name some types of Arthritis?

A
  • Osteoarthritis
  • Rheumatoid arthritis
  • Gouty Arthritis
  • Infectious
  • Juvenile Idiopathic
  • Secondary to systemic disease

There are a few more

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10
Q

What is the most common type of arthritis?

A

Osteoarthritis

Associated with increased age and obesity. Progressive deterioration. Usually in weight baring joints.

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11
Q

What’s Primary and Secondary Osteoarthritis?

A
  • Primary (most common): no initial cause

- Secondary: at any age, previous joint trauma or congenital abnormality.

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12
Q

Who’s at risk of getting osteoarthritis???

A
  • Older people
  • Female (post menopause)
  • Obesity
  • Pre-existing joint deformity
  • Excess echanical stress (sports people, miners, farmers)
  • Genetic susceptibility
  • Hypermobility
  • Other diseases (secondary OA)
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13
Q

Features/ Symptoms of Osteoarthritis?

A
  • Morning stiffness
  • Pain, worse at night
  • Reduced range of movement
  • Progressive reduction in mobility
  • joint effusion (fluid)
  • Crepitus (grating sensation)
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14
Q

What’s Heberden’s node and Bouchard’s node?

A

It’s swelling/ deformities of the joints in the fingers

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15
Q

What’s an Osteophytes

A

It’s a bony projection associated with the degeneration of cartlidge and joints. Symptoms of osteoarthritis

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16
Q

What disease is this describing?

  • Inflammation in synovium
  • Thickened membranes
  • Chronic inflammation leads to cartelidge and joint destruction
  • Other tissues involved such as lungs, vessels
A

This is Rheumatoid Arthritis

  • Familial association
  • Link with HLA (human leukocyte antigen)
  • Women 3x more than men.
  • 1% of population
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17
Q

Features/ symptoms of rheumatoid arthritis?

A
  • Small joints usually affected (hands/ feet)
  • Pain
  • Swelling/ deformity
  • Fever, fatigue, generalised pain
  • Joints often stiff without prior activity
  • Most have fluctuating disease
18
Q

What is swan neck deformity? And what disease is it associated with?

A

It’s bending of the fingers resulting in them resembling the shape of swan’s necks. It’s associated with rheumatoid arthritis.

19
Q

What is Boutonniere deformity? And what disease is it associated with?

A

It’s a deformity of the hands and feet where the joints near knuckle are bent in. And joints furthest from the knuckle are bent out.
Caused by rheumatoid arthritis.

20
Q

What symptoms are needed to diagnose someone whith rhematoid arthritis? (need 4)

A
  • Morning stiffness
  • Arthritis in 3 or more joints
  • Arthritis of typical hand joints
  • Symmetric Arthritis
  • Rheumatoid nodules
  • Serum rheumatoid factor
  • Typical radiographic changes
21
Q

What joint disorder is associated with crystal accumilation in the joints?

A

Crystal Arthropathies

gout/ pseudogout

22
Q

What is Crystal Arthropathies?

A

It’s a condition where small crystals form in the joints.

23
Q

What condition is characterised by:

Raised uric acid

A

Gout

Urate deposits as crystals in the joints. Repeated attacks lead to arthritis.

24
Q

What is GOUT?

A

It’s a form of Crystal arthropathies. Raised uric acid deposits itself in the joints as crystals. Can cause arthritis.

25
What can cause GOUT?
- Drugs (aspirin, diuretics) - Alcohol - Renal disease - Hypothyroidism - Dehidration
26
Name some features of GOUT (form of crystal arthropathies)
- Sudden onset of excruciating burning joint pain - Redness, warmth, tenderness, stiffness - Usually first attack involves big toe - Subsequent attacks are less severe.
27
What's another name forCalcium pyrophosphate crystal deposition disease?
Pseudogout
28
What's Pseudogout? (Calcium pyrophosphate crystal deposition disease)
Its calcium pyrophosphate crystals in connective tissue. Crystals can enlarge and rupture causing crystal shedding into joint cavity and soft tissue. Usually in knees and ankles.
29
How do you get pseudogout?
- Can be hereditaty - Associated with osteoarthritis - Trauma/ surgery - More common with increasing age
30
What is the name given for inflammation of a joint caused by bacterial infection? Commonly in the knee.
Septic Arthrits
31
What's septic arthritis?
It's inflammation of a joint caused by bacterial infection commonly affects the knee. Causes pain, swelling, redness, heat, difficulty moving. some have high temp too. Symptoms develop quickly
32
Symptoms of Septic Arthritis?
- Severe pain - Swelling - Redness - Heat - Some have high temperature Symptoms develop quickly over hours/ days
33
How do you treat septic arthritis?
- Needs IV antibiotics - May require washout of joint Can be serious and cause sepsis
34
What's Osteomyelitis?
It's a bone infection caused by bacteria. Happens often in trauma/ surgery where there's a presence of foreign bodies. More risk in diabetics. Haematogenous spread
35
TRUE or FALSE: The most common bone tumour is a neoplam?
FALSE The most common bone tumour is metastatic disease from a distant cancer eg-Prostate, Kidney, Breast. Primary bone tumours are relatively rare.
36
Name some benign and malignant Bone Tumours...
BENIGN: osteiod, osteoma MALIGNANT: sarcoma
37
What are the 3 types of muscle in the body?
- Skeletal - Smooth - Cardiac
38
What's another name for Skeletal muscle, and what are it's properties?
STRAITED MUSCLE called this because of visible striations on microscopy. Involed in voluntary movements - beceps, arm muscles, leg muscles.
39
Features of Smooth muscle...
- Forms muscle layer in walls of GIT, ducts, arteries and internal organs - Involuntary actions such as bowel peristalsis - Controlled by ANS
40
What type of muscle is affected by muscular dystrophies and neuromuscular disorders?
Skeletal muscle | straited muscle
41
What type of muscle is affected by Leiomyomas?
Smooth muscle