Mutation Flashcards
(3 cards)
What is a mutation
Mutations are permanent changes in DNA sequences of gene
1. Germline — gametes, passed on, sickle cell anemia
2. Somatic — body cells, not passed on, most cancers
How are mutation caused: Spontaneous mutations
Spontaneous mutations: errors caused during DNA replication
such as..
• repositioning of hydrogen on nitrogen base
• the removal of a amino group (NH2)
• replication slipped strand
How are mutations caused: induced mutation
induced mutation: caused by mutagenic agents
Such as..
• chemicals - cigarettes, drugs
• UV radiation
• x rays