Myasthenia Gravis Flashcards
(47 cards)
what is Myasthenia Gravis
it is a complex autoimmune disorder where the antibodies destroy the neuromuscular connections
what problems does MG cause?
causes problems with the nerves that communicate with muscles
what does MG affect
the voluntary muscles of the body like the
- eyes
- mouth
- throat
- limbs
weakness and rapid fatigue of the muscle under voluntary control is usually characteristic of what diorder
Myasthenia Gravis
is there a cure for MG
no
some symptoms of MG
- droopy eyelids
- weakness of arms and legs
- double vision
- difficulties speaking, chewing, swallowing, and breathing
MG is common in who
women younger then 40 and men older than 60
what are the three types of MG in children?
- Congenital MG
- Transient Neonatal MG
- Juvenile MG
which kind of MG is this:
a very rare non immune for of MG that is inherited as an autosomal receive disease. SO in this case both males and females are affected equally. There are two copies of the gene because you inherit one from mom and one from dad. MUST HAVE BOTH. Symptoms will usually being in the first year of baby and are life long
Congenital MG
Which kind of MG is this:
This is when 10-20% of babies who are born to a mother who currently has MG, temporarily have MG themselves. This happens when antibodies that are similar to MG cross the placenta to the developing fetus. This only last for a few weeks and the baby does not have a greater likelihood to develop this disease later in life.
Transient Neonatal MG
Which kind of MG is this:
this develops quickly in females adolescents (caucasian) and it is an autoimmune disorder. This is life long and may go in and out of remission.
Juvenile MG
10% of MG cases are?
Juvenile onset
symptoms for babies with transient neonatal MG
- poor sucking
-weakness
-respiratory difficulty - this goes away after antibodes disappear
some babies may need a mechanical breathing machine
Congenital MG symtoms
- weakness in arms and legs
- delayed motor skills like crawling, sitting, walking
- difficulty feeding
- weak eyelids
- poor head control
Juvenile MG symptoms
- fatigue
- problems chewing and swallowing
- droop eyelids
what is the first sign and symptom in more than 1/2 of the people with MG
eye problems
ptosis
drooping of one or both eyes
diplopia
double vision (horizontal or vertical)
eye problems associated with MG
- ptosis
- diplopia
- blurred vision
Fascial and throat problems with MG include
- speech difficulty
- swallowing difficulty
- chewing difficulty
- fascial expression (lost smile)
in what percent of people is fascial and throat problems the first symptom in MG
15%
Arm and leg problems with MG
- weakness
- arms are affected more then legs
- waddle walking (legs affected)
you should see a doctor for MG if…
having difficulty
- breathing
- seeing
- swallowing
- chewing
- walking
how many of the symptoms does a patient have to have for MG to be predicted?
at least 2
