Myology Flashcards

(50 cards)

1
Q

what are the functions of the muscular system

A

locomotion
vasoconstriction and vasodilation
peristalsis
cardiac motion
posture maintenance
heat generation
stabilize joints

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2
Q

vasoconstriction and vasodilation

A

constriction and dilation of blood vessel walls are the results of smooth muscle contraction

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3
Q

peristalsis

A

wavelike motion along digestive tract produced by the smooth muscle

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4
Q

posture maintenance

A

contraction of skeletal muscles maintains the body posture and muscle tone

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5
Q

heat generation

A

75% ATP energy used in muscle contraction is released as heat

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6
Q

stabilise joints

A

even as they pull on bones to cause movement they strengthen and stabilise the joints of the skeleton

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7
Q

properties of skeletal, cardiac and smooth muscles

A

striation
nucleus
transverse tubule
intercalated disk
control

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8
Q

striation

A

only present in skeletal and cardiac uscles
absent in smooth

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9
Q

nucleus

A

smooth and cardia are uni-nucleated
skeletal are multi-nucleated

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10
Q

transverse tubule

A

well developed in skeletal and cardiac muscles to transport calcium
absent in smooth muscle

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11
Q

intercalated disk

A

specialised intercellular junction that only occurs in cardiac muscle

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12
Q

control

A

skeletal muscle is always under voluntary control
some exceptions such as tongue and pili arrector
smooth and cardiac are under involuntary control

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13
Q

describe skeletal muscle

A
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14
Q

describe cardiac muscle

A
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15
Q

describe smooth muscle

A
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16
Q

components of muscles

A

epimysium
muscle fascicle
muscle fibre
myofibrils
sarcolemma
sarcoplasm
sarcoplasmic reticuluum

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17
Q

epimysium

A

outer layer of connective tissue covering an entire muscle

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18
Q

muscle fascicle

A

bundle fo skeletal muscle fibres surrounded by perimysium

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19
Q

muscle fibre

A

surrounded by a thin layer of connective tissue the endomysium
contains several hundred to thousand myofibrils

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20
Q

myofibrils

A

composed of myofilaments (actin and myosin)

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21
Q

sarcolemma

A

thin membrane enclosing skeletal muscle fibre

22
Q

sarcoplasm

A

intracellular fluid between myofibrils

23
Q

sarcoplasmic reticulum

A

specialised endoplasmic reticulum of skeletal muscle

24
Q

what is the triad and what is it composed of

A

each t tubule runs between pair of sacs formed by sarcoplasmic reticulum fusion
terminal cistern

can act as conduit for action potentials but no direct connection

25
myofibril structure
composed of actin and myosin light bands are only actin, I bands, isotropic to polarised light dark bands are myosin filaments and ends of actin filaments, A bands, anisotropic to polarised light
26
2 different bands
I and A which are light and dark respectively
27
light bands
I bands only actin filaments isotropic to polarised light
28
dark bands
A bands myosin filaments and ends of actin filaments anisotropic to polarised light
29
what is a Z disk
filamentous protein
30
segment of myofibril between 2 successive Z disks is called what
sarcomere
31
what is Titin
filamentous molecule to keep myosin and actin filaments in place
32
what is a myofibril comprised of
actin and myosin
33
what is an actin filament composed of
actin troponin tropomyosin
34
structure of an actin filament
backbone of actin is double stranded F-actin protein 2 strands wound in helix each strand of F is composed of G actin molecules one ADP attached per one G-actin ADP believed to be active sites bases of actin filaments inserted into the Z disks
35
label the image
36
tropomyosin
another protein component of actin filament wrapped spirally around sides of F-actin lies on active sites of actin strands
37
what does troponin have
3 subunits T,I and C
38
troponin T
strong affinity for tropomyosin
39
troponin I
strong affinity for actin (inhibition)
40
troponin C
strong affinity for calcium ion
41
myosin structure
2 heavy chains and 4 light chains 2 heay wrap around to form double helix, called tail end of each is folded bilaterally into globular polypeptide called myosin head light chains help function during muscle contraction
42
label the image
43
2 main types of synapses
chemical electrical
44
chemical synapses
synaptic cleft neurotransmitters skeletal muscles
45
electrical synapses
gap junction cardiac ventricular muscle in the uterus and in the bladder
46
which type of synapse is this
chemical
47
which type of synapse is this
electrical
47
which type of synapse is this
electrical
48
nerve excitation process
Action potentials are propagated down the motoneuron Calcium entry into the presynaptic terminus Release of Ach from synaptic vesicles, diffusion across synaptic cleft and binding with post-synaptic receptors ACh diffuses across the synaptic cleft to the postsynaptic membrane. This specialized region of the muscle fibre is called the motor end plate, which contains nicotinic receptors for ACh Opening of Na+ /K+ channels on post-synaptic membrane Postsynaptic membrane depolarization (End Plate Potential) Ach breakdown via acetyl cholinesterase
49
label the image of the synthesis and degradation of acetylcholine