Nacrotic analgesics

Question 1

what are Phenantherene Opium Alkaloids

Answer 1

morphine

codiene

Question 2

what are Semisynthetic Morphine Derivatives

Answer 2

Di-acetyl morphine (heroin)

Question 3

what are Synthetic Morphine Substitutes

Answer 3

fentayl

meperdine

Question 4

what are Mixed Agonist-Antagonist Narcotic Analgesics

Answer 4

nubain (nalbuphine)

Question 5

Talk about morphine absorption

Answer 5

1

Question 6

Talk about morphine distribution

Answer 6

1

Question 7

what is the drug that treat neontal asphyxia

Answer 7

naloxane

Question 8

What does morphoine lead during pregency & labour

Answer 8

Preg : addicition

Labour : neontal asphyxia

Question 9

Talk about codiene absorption

Answer 9

1

Question 10

Oral biovilability of morphine & codiene

Answer 10

morphibe :25-30

codiene : 50

Question 11

Talk about excretion & metabolism of morphine

Answer 11

1

Question 12

Talk about duration of morphine & codiene

Answer 12

morphine :6-8 hrs

codiene : 2-4 hrs

Question 13

what is percentage of opium at morphine & codiene

Answer 13

morphine :10

codiene : 1

Question 14

what are opiate receptors and their causes

Answer 14

1

Question 15

who lead to constipation at opoid receptorrs

Answer 15

muu & delta

Question 16

What are affects of morphine on CNS

Answer 16

11

Question 17

what are effects of morphine peripheary

Answer 17

1

Question 18

Talk about tolerance of morphine

Answer 18

1

Question 19

What does histamine release lead to

Answer 19

skin: itching & triple affect

R.C :bronchospasm

Question 20

What does increase of A.D.H lead to

Answer 20

oligria

Question 21

Talk about affects of codiene

Answer 21

potent : anti-tussive

weaker than morphine

Question 22

what are therupatic uses of morphine

Answer 22

1

Question 23

what are therupatic uses of codiene

Answer 23

1

Question 24

what are drugs that are taken with codiene in visceral pain cases

Answer 24

asprin & paracetamol

Question 25

what are adverse affects of morphine

Answer 25

10

Question 26

what is the affect of large dose of morphine

Answer 26

decreasing vomiting center

Question 27

what is the affect of small dose of morphine

Answer 27

increasing C.T.Z : vomiting & nausea

Question 28

Talk about acute morphine poising

Answer 28

Manifestations Death Treatment

Question 29

What is the affect of pure O2

Answer 29

apnea

Question 30

what are the elements that used at stomach wash of mrophine

Answer 30

K-permengenate+charocal+MGSO4

Question 31

what is specific morphinic antagonist

Answer 31

naloxane

Question 32

Talk about chronic poisiong of morphine

Answer 32

``` Tolerance Due to Addict Sudden stop Managment ```

Question 33

What is the drug that is gradual substitutent for morphine

Answer 33

methadone

Question 34

Talk about contradictions of morphine

Answer 34

``` 12:- Head injury Acute abdomen Intra cranial tension Pregnency & labour Liver disease Extreme age Myxdema Allergy History of addiction Alone with colic Respiratory diseaes Eplipsey ```

Question 35

Talk about mepierdiene kinetics

Answer 35

50% orally bioavillability Duration Onset

Question 36

Talk about mepiderne dynamics

Answer 36

``` 4 less 4 no Local Large dose ADH Atropine like Drug interaction Antagonized by naloxane ```

Question 37

Who is weaker than morphine by 1/5

Answer 37

codiene

Question 38

Who is lesser than morphine by 1/10

Answer 38

mepridene

Question 39

who is better than morphine at pre-anesthetic medication

Answer 39

mepridene

Question 40

Talk about therupatic uses of mepridene

Answer 40

Obestric anesthesia Alone in colic Pre anesthetic medication Severe visceral

Question 41

example about CNS depressents

Answer 41

Benzodizpiens

Question 42

Talk about naloxane

Answer 42

``` Block actions No effects on CNS depressents Pure antagonists selective on muu receptors 1 hour should be repeated Therupatic uses : 3 ```