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NB 3 Block Flashcards

(62 cards)

1
Q

Kluver-Bucy Syndrome in Humans

A

Lesions to the Limbic System:
-Bilateral Glioma
-Head Trauma
-Status epilepticus
-Herpes simplex encephalitis
-Post epilepsy surgery

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2
Q

Sedative-related (sedatives/hypnotics/anxiolytics [anxiety-reducing]) drugs

A

Class of Drug:
-Benzodiazepines
-Sleep-promoting non-benzodiazepines
-Barbiturates
-Dual orexin receptor antagonists (DORAs)
-Other sedatives

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3
Q

Diazepam, Alprazolam, Temazepam, Clonazepam, Lorazepam, Chlordiazepoxide

A

Benzodiazepines

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4
Q

Sleep-promoting non-benzodiazepines

A

Zolpidem

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5
Q

Phenobarbital, secobarbital

A

Barbiturates

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6
Q

Daridorexant (for insomnia)

A

Dual orexin receptor antagonists (DORAs)

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7
Q

Sodium Oxybate

A

Other Sedatives

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8
Q

Fluoxetine, Paroxetine, Sertraline, Citalopram

A

Selective Serotonin reuptake inhibitors (SSRIs)

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9
Q

Antidepressants

A

-Selective Serotonin reuptake inhibitors (SSRIs)
-Serotonin-norepinephrine reuptake Inhibitors (SNRIs)
-Tricyclic antidepressants (TCAs)
-Monoamine oxidase inhibitors (MAOIs)

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10
Q

Fluoxetine, Paroxetine, sertraline, citalopram

A

Selective serotonin reuptake inhibitors (SSRIs)

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11
Q

Venlafaxine, duloxetine

A

Serotonin-norepinephrine reuptake Inhibitors (SNRIs)

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12
Q

Imipramine, amitriptyline, clomipramine

A

Tricyclic antidepressants (TCAs)

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13
Q

Phenelzine, selegiline

A

Monoamine oxidase inhibitors (MAOIs)

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14
Q

Mood Stabilizers

A

Class of Drug: Mood stabilizers

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15
Q

Lithium, valproate (anticonvulsant); carbamazepine (anticonvulsant); olanzapine (atypical antipsychotic); quetiapine (atypical antipsychotic)

A

Mood stabilizers

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16
Q

Antipsychotics (neuroleptics)

A

Class of Drug:
-Traditional (first generation)
-Atypical (second generation)

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17
Q

Chlorpromazine, haloperidol

A

Traditional (first generation)

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18
Q

Clozapine, risperidone, olanzapine, quetiapine, brexpiprazole, lurasidone

A

Atypical (second generation)

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19
Q

Donepezil, rivastigmine, galantamine

A

Cholinesterase inhibitors

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20
Q

Memantine

A

NMDA receptor blockers

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21
Q

Lecanemab

A

Monoclonal antibodies (MAB)

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22
Q

Drugs used to treat Alzheimer’s Disease

A

Class of Drug:
-Cholinesterase inhibitors
-NMDA receptor blockers
-Monoclonal Antibodies (MAB)

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23
Q

Stimulants and Stimulant-Like Drugs

A

Class of Drug:
-Stimulants
-Norepinephrine reuptake inhibitors (NRIs)
-Wake promoting drugs

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24
Q

Methylphenidate, amphetamine, dextroamphetamine, lisdexamfetamine, methamphetamine, cocaine, MDMA (Ecstasy)

A

Stimulants

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25
Atomoxetine, viloxazine
Norepinephrine reuptake inhibitors (NRIs)
26
Modafinil
Wake promoting drugs
27
Opioids (class of drug)
Heroin, Morphine, Codeine, oxycodone, fentanyl, methadone
28
Hallucinogens and Related Drugs
Class of Drug: -Hallucinogens -Cannabis -Dissociative anesthetics
29
Hallucinogens
Lysergic acid diethylamide (LSD), mescaline, psilocybin
30
Marijuana, hashish
Cannabis
31
Phencyclidine (PCP), ketamine, esketamine
Dissociative anesthetics
32
Treatment of Substance-Related Disorders
Class of Drug: -Alcohol use disorder -Benzodiazepine overdose -Nicotine use disorder -Opioid overdose -Opioid use disorder-abstinence therapy -Opioid use disorder--replacement therapy
33
Naltrexone (as above), disulfiram, acamprosate
Treatment for alcohol use disorder
34
Flumazenil (GABA antagonist)
Treatment for Benzodiazepine overdose
35
Flumazenil (GABA antagonist)
Treatment for Benzodiazepine overdose
36
Treatment for Nicotine use disorder
Varenicline, bupropion
37
Treatment for Opioid overdose
Naloxone
38
Treatment for opioid use disorder-abstinence therapy
Naltrexone
39
Treatment for Methadone, buprenorphine
Opioid use disorder-replacement therapy
40
Respiratory stimulants
Acetazolamide (for central sleep apnea)
41
Anti-androgens
Medroxyprogesterone acetate (for paraphilias)
42
Beta-blockers
Propranolol (for acute symptoms related to anxiety)
43
Lesion to the Prefrontal (Phineas Gage, trans-orbital lobotomies)
-Emotional disinhibition -Emotional flattening, increased docility -Decreased goal-oriented behavior
44
Brain Region responsible for fear response
the amygdala
45
The ventromedial prefrontal cortex (PFC) is responsible for:
Down-regulation of fear/extinction learning
46
The orbitofrontal cortex is responsible for:
long term fear memory
47
The amygdala is responsible for
fear learning
48
Prefrontal Cortex is responsible for
Inhibition
49
Paramnesia
Involves distorted memory or confusions of fact and fantasy, such as in confabulation or deja vu
50
Paraphasic
Mistakes in lexical access such as expressing the word "pen" instead of "pencil"
51
Phonemic paraphasia
Expressing the word "eletump" instead of "elephant"
52
Loquacious
Very talkative--typically found in Wwernicke's aphasia
53
Dysarthric
Abnormalities in speech articulation, due to impaired control of muscles of vocalization
54
Transcortical aphasia
Fluent but abnormal speech in the context of normal repetition
55
Which of the following best describes the harm risk and medical usefulness of cannabis per federal regulations?
High harm risk and no safe and accepted uses in medicine
56
An approved smoking cessation drug with possible side effects of unpredictable and erratic behaviors--drug most likely prescribed:
Varenicline
57
Lethargic
Patient can be fully aroused
58
Obtunded
Patient cannot be fully aroused
59
Stuporous
Sleep-like status
60
Comatose
No purposeful response to stimuli
61
A 35 y/o man is brought to the ED b/c of injuries incurred during a MVC. The man is unconscious. Which of the following breathing patterns is most likely linked to a grave outcome? A. Tidal Breathing B. Hypoventilation C. Neurogenic Hyperventilation D. Ataxic Breathing E. Cheyne-stokes breathing
D. Ataxic breathing
62