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Flashcards in neoplasm - conditions Deck (88)
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1

ulcerative colitis - neoplasm

colon adenocarcinoma

2

chronic atrophic gastritis - neoplasm

it predisposes to gastric adenocarcinoma

3

postsurgical gastric remnants - neoplasms

it predisposes to gastric adenocarcinoma

4

aids predispose to (neoplasm)

1. aggressive lymphoma (non-Hodgkin)
2. Kaposi sarcoma

5

Down syndrome - neoplasm

ALL, AML

6

immunodeficiency predisposes to (neoplasm)

1. lymphoma
2. melanoma
3. renal cell carcinoma
4. SCC of skin

7

Li-Fraumeni syndrome predisposes to (neoplasm)

various cancers at young age (eg. sarcoma, breast, leukemia, adrenal gland)

8

radiation exposure - high risk of developing (neoplasm)

leukemia, sarcoma, papillaty thyroid cacner, breast cancer

9

actinic keratosis - precursor to (neoplasm)

squamous cell carcinoma of the skin

10

paget disease of bone predisposes to (neoplasm)

1. osteosarcoma
2. fibrosarcoma

11

dematomyositis predisposes to (neoplasm)

visceral malignancy (particularly genitourinary)

12

polymyositis predisposes to (neoplasm)

visceral malignancy (particularly genitourinary)

13

dermatomyositis and polymyositis predispose to visceral malignancy particularly

genitourinary

14

Xeroderma pigmentosum predisposes to

skin cancer (BCC, SCC, melanoma)

15

Oncogenes role in cancer

gain of function --> increase cancer risk

16

oncogenes and cancer - need damage ... allele (number)

only 1

17

tumor suppressor genes role in cancer

loss of function --> increase cancer risk

18

tumor suppressor genes and cancer - need damage ... allele (number)

both allele

19

BCR-ABL - oncogene or tumor suppressor gene?

oncogene

20

RET - oncogene or tumor suppressor gene?

oncogene

21

RAS - oncogene or tumor suppressor gene?

oncogene

22

APC - oncogene or tumor suppressor gene?

tumor suppressor gene

23

Rb - oncogene or tumor suppressor gene?

tumor suppressor gene

24

NF1 - oncogene or tumor suppressor gene?

tumor suppressor gene

25

NF2 - oncogene or tumor suppressor gene?

tumor suppressor gene

26

c-myc - oncogene or tumor suppressor gene?

oncogene

27

c-kit - oncogene or tumor suppressor gene?

oncogene

28

BRAF - oncogene or tumor suppressor gene?

oncogene

29

DCC - oncogene or tumor suppressor gene?

tumor suppressor gene

30

MEN1 - oncogene or tumor suppressor gene?

tumor suppressor gene