oncogenic microbes and carcinogens Flashcards Preview

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Flashcards in oncogenic microbes and carcinogens Deck (88)
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1

oncogenic microbes - types

1. EBV 2. HBV 3. HCV 4. HHV-8
5. HPV 6. H. pylori 7. HTLV-1
8. Liver fluke (Clonorchis sinensis)
9. Schistosoma hamatobium

2

neoplasm - H. pylori causes

1. Gastric adenocarcinomas
2. MALT lymphomas

3

neoplasm - HCV causes
neoplasm - HBV causes

hepatocellular carcinoma + LYMPHOMA

4

neoplasm - HHV-8 causes

kaposi sarcoma

5

neoplasm - Liver fluke (Clonorchis sinensis)

cholangiocarcinoma

6

neoplasm - Schistosoma hamatobium causes

Bladder cancer (SCC)

7

neoplasm - HTLV-1 causes

adult T-cell leukemia/lymphoma

8

neoplasm - HPV causes

1. cervical and penil/anal carcinoma (types 16 and 18)
2. head and neck cancer

9

neoplasm - EBV causes

1. Burkitt lymphoma
2. Hodgkin lymphoma
3. nasopharyngeal carcinoma
4. primary CNS lymphoma (in immunocompromised patients)

10

aflatoxin source

Aspergillus

11

carcinogens - aflatoxins (Aspergillus) causes

hepatocellular carcinoma

12

carcinogens - Alkylating agens causes

leukemia/lymphoma

13

carcinogens - aromatic amines causes (and examples)

Transitional cell carcinoma of the bladder
(benzidine, 2- naphthylamine)

14

aromatic amines - examples

- benzidine
- 2- naphthylamine

15

carcinogens - arsenic causes

1. angiosarcoma of the liver
2. lung cancer
3. SCC of the skin

16

carcinogens - asbestos causes

Bronchogenic ca> mesothelioma

17

carcinogens - vinyl chloride

liver angiosarcoma

18

carcinogens - Radon causes

lung cancer

19

carcinogens - carbon tetrachloride causes

LIVER - centilobular necrosis, fatty changes

20

carcinogens - Nitrosamines - examples

smoked foods

21

carcinogens - Nitrosamines causes

gastric cancer

22

carcinogens - ionizing radiation

papillary thyroid carcinoma

23

carcinogens - ethanols

1. SCC of esophagus
2. hepatocellular carcinoma

24

carcinogens - cigarrete smoke causes

1. transitional cell ca of bladder
2. cervical ca
3. SCC of esophagus
4. adenoca of esophagus
5. Renal cell ca
6. SCC of the larync
7. SCC of the lung
8. small cell ca of the lung
9. pancreatic adenoca

25

cholangiocarcinoma - microbe

chlonorchis sinensis

26

head and neck cancer - microbe

HPV

27

nasopharyngeal carcinoma - microbe

EBV

28

carcinogens that cause angiosarcoma of the liver

1. arsenic
2. vinyl chloride

29

carcinogens that cause hepatocellular carcimoma

1. aflatoxin (Aspergillus)
2. ethanol

30

carcinogens that cause tramsitional cell carcinoma of the bladder

1. Cigarette smoke
2. Aromatic amines