Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Parasit E5 > Neospora & Sarcocystis > Flashcards

Neospora & Sarcocystis Flashcards

1
Q

what is the domestic host of neospora

A

canines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

is neospora zonotic

A

NO!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is the IH for neospora

A

domestic livestock, grazing wildlife, dogs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

how does IH become infected neospora

A

oocysts shed in environment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

can vertical transmission of neospora occur in IH?

A

yes!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

how does DH become infected neospora

A

ingestion of tissue cysts from IH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what lifecycle does neospora have

A

mostly indirect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

t/f sexual multiplication occurs in IH

A

FALSE, only in DH
asexual in IH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what clinical signs will canines have neospora

A

neuromuscular disease
congenital infection
posterior paresis
due to exposure to cow fetuses/ placenta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

clinical signs in cattle neospora

A

reproductive disease
history of abortion
disease of placenta/fetus
-primary infection in dam
-neuromuscular disease in congenitally infected calves

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

is there an fda treatment for neospora in cattle or dogs

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

how to control canine infection neospora

A

do not allow access to fetal or placental tissues
do not feed raw meat
do not breed females previously diagnosed with clinical disease/ whelped litters with affected puppies
avoid immunosuppressive therapies in seropositive dogs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

how to control cattle infection neospora

A

restrict dog access to feed
observe for signs of reproductive loss
keep herd productivity records
remove fetal/placental tissues
closed hers
cull seropositive cows (controversial)
serological assessment is suspect outbreak

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

toxoplasma vs neospora DH

A

toxo: cats, shed MANY oocysts one time
neo: dogs, shed FEW oocysts many times

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

toxoplasma vs neospora lifecycle

A

toxo: oocyst to DH and tissue cyst in variety of IH
neo: no oocyst to DH, viable tissue cysts in narrow range IH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

toxoplasma vs neospora zoonotic?

A

toxo: YES
neo: NO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

toxoplasma vs neospora risk for congenital infection

A

toxo: only during primary infection when pregnant, all other pregnancies protected
neo: lifetime risk of congeital infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

toxoplasma vs neospora impact on cattle production

A

toxo: none
neo: major source production losses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what kind of lifecycle in sarcocystis sp

A

obligate indirect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

how is sarcocystis sp spread

A

ingestion of tissue cysts in SPECIFIC IH

21
Q

what are the DH of sarcocystis sp

A

dogs, cats, humans

22
Q

does sexual replication occur in DH or IH for sarcocystis sp?

A

DH, no asexual at all!

23
Q

where does sexual replication occur sarcocystis sp

A

small inetestine

24
Q

are there clinical signs in DH for sarcocystis sp

A

NO

25
Q

is there human/animal associations for sarcocystis sp

A

YES

26
Q

does disease occur in DH or IH or both in sarcocystis sp

A

IH only

27
Q

what type of replication occurs in IH sarcocystis sp?

A

asexual only!

28
Q

where does replication occur in IH sarcocystis sp

A

striated muscles of endothelial cells

29
Q

sarcocystis cruzi is a relationship between which species

A

dog DH and cattle IH

30
Q

how does dog get infected with sarcocystis cruzi? how does it spread this diease?

A

ingest tissue cysts in cattle
sporocysts shed in feces

31
Q

how do cattle get infected with sarcocystis cruzi? how does it spread this disease?

A

ingest sporocysts while grazing
2 generations of asexual replication
sarcocysts in striated muscle fibers

32
Q

t/f in sarcocystis cruzi dogs will have clinical disease

A

FALSE, no clinical disease

33
Q

what health effects will be in cattle for sarcocystis cruzi?

A

abortion, stillbirth
fever, anorexia, diarrhea, muscle spasm, loss of tail hair, hyperexcitability
calves that survive acute infection fail to thrive, premature death

34
Q

is treatment of sarcocystis cruzi economically practical

A

no

35
Q

how to mitigate risk of sarcocystis cruzi

A

exclude dogs from production facilities
periodic fecal exam on dogs

36
Q

equine protozoa myloencephalitis primary etiologic agent

A

sarcocystis neurona

37
Q

what is the DH for sarcocystis neurona

A

opossum

38
Q

how does the DH spread sarcocystis neurona

A

sporocysts in feces

39
Q

t/f horses are an IH of sarcocystis neurona

A

false! accidental host

40
Q

how do horses become infected with sarcocystis neurona

A

ingestion of sporocysts in contaminated feed/ pasture

41
Q

what are clinical signs of sarcocystis neurona

A

neurologic disease
stumbling, lameness, paresis, muscle atrophy
urinary incontinence, constipation

42
Q

how do you diagnose sarcocystis neurona

A

serology
IgG Ab
IFA testing to distinguish causative agent

43
Q

t/f seropositivity equates to disease

A

false, it does not !

44
Q

is EPM disease rare?

A

yes

45
Q

what could seropositivity indicate?

A

risk to subsequently developing disease

46
Q

treatment considerations for sarcocystis neurona

A

recognize phenotypes and response to treatment is promising
contain parasite replication and not curative
prophylactic drug questionable value and expensive!

47
Q

ponazuril target

A

mitochondria to disrupt amino aid synthesis and energy metabolism
cross BBB inot CSF

48
Q

sulfadiazine/ pyrimethamine tagrer

A

interfere w parasite synthesis of folic acid and inhibit energy metabolism
must replace folic acid deficiency in host
possible toxicity from long term use

Parasit E5 (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions