Nerves Flashcards

1
Q

Subdivision of nervous system

A

CNS and PNS

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2
Q

CNS

A

Brain and spinal cord

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3
Q

PNS

A

Somatic and Autonomic

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4
Q

Somatic

A

Voluntary control ( skeletal muscle)

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5
Q

Autonomic

A

Sympathetic and Parasympathetic

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6
Q

Brain

A
Meninges
Gyrus and sulcus
Cerebellum
Cerebrum
Diencephalon
Brainstem
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7
Q

Meninges

A

Dura
Arachnoid
Pia

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8
Q

Gyrus

A

Folds

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9
Q

Sulcus

A

Grooves

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10
Q

Cerebrum

A

Frontal
Occipital
Parietal
Temporal

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11
Q

Diencephalon

A

Hypothalamus- homeostasis

Thalamus- sensory

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12
Q

Brainstem

A

Mid-brain
Pons
Medulla Oblongata

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13
Q

Spinal cord has ____ pairs of spinal nerves

A

31

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14
Q
\_\_\_ cervical
\_\_\_\_ thoracic
\_\_\_\_\_ lumbar
\_\_\_\_ sacral
\_\_\_\_\_ coccygeal
A
8
12
5
5
1
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15
Q

Grey Matter=

A

Dorsal horn
Ventral horn
Lateral horn

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16
Q

Neuron structure

A

Cell body (soma)
Dendrites (receive information)
Axons (sends action potential)/(release transmitter)

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17
Q

Types of neuron

A

Glia- astrocytes, oligodendrocytes

Microglia- phagocytic

18
Q

Resting Membrane Potential

19
Q

What maintains the RMP

A

Leaky channels
Na+/K+ pump
Large intracellular -ve charged molecules

20
Q

Equilibrium potential

A

The membrane potential at which the electrical gradient is exactly equal and opposite to concentration gradient

21
Q

Hyperpolarisation

A

More negative

22
Q

Depolarisation

A

More positive

23
Q

Action Potentials

A

Transmit signals over long distances

24
Q

Graded Potential

A

Decides when an action potential should be fired

25
Resting membrane potential
keeps cell ready to respond
26
Action potential process
1. cell stimulated up to threshold (graded) 2. depolarisation 3. repolarisation 4. hyperpolarisation 5. back to resting potential
27
Graded Potential
``` Generated by ligand gated channels End plate potential at NMJ Can occur due to hyperpolarisation or depolarisation Decremental Non-propagated Amplitude determines stimulus ```
28
Fast EPSP (ionotropic)
Release of glutamate Surge in Na+ Depolarisation
29
Fast IPSP (ionotropic)
Release of GABA Cl- cells enter Hyperpolarisation
30
Slow EPSP
Release of glutamate Binds to G protein Closes some leaky K+ channels Prevents cell returning to RMP
31
Slow IPSP
Neurotransmitter binds to G protein Activates G protein and causes K+ ions to flow out of cell Which leads to hyperpolarisation
32
Action Potential
``` Have threshold They are all or none Voltage gates ion channels Cannot encode amplitude only frequency Cannot summate self-propagate Have refractory period ```
33
Compound Action Potential
Graded | Summation of many APs from different axons (myelinated and unmyelinated)
34
Fastest conducting axons
Ia Muscle spindle
35
Slowest conducting axons
IV pain and heat
36
tetrodotoxin
blocks Na+ channels and blocks AP
37
Joro spider toxin
blocks Ca+ channels and stops transmitter release
38
Botulinum toxin
disrupts the release of transmitter
39
Curare
blocks Ach receptors and prevents end-plate potential
40
anticholinesterase
blocks removal of acetylcholine