neural crest Flashcards
(9 cards)
What forms during neurulation from the thickening of the ectoderm?
Neural plate
The neural plate is the precursor to the neural tube.
What does the neural plate fold to create?
Neural tube
The neural tube later develops into the brain and spinal cord.
What are the key signaling molecules that induce neural crest formation in the ectoderm?
BMP, Wnt, FGF
These signaling molecules play a crucial role in the development of neural crest cells.
What happens to cells at the edges of the neural plate during neural crest migration?
They detach and migrate to different parts of the body
These cells differentiate into various tissues.
Which transcription factors are activated once the neural crest is specified?
Pax3, Pax7, Zic1
These factors determine neural crest cell differentiation.
Name additional transcription factors that refine the fate of neural crest cells.
Foxa3, Sox9, Snail
These factors further influence the differentiation of neural crest cells.
What role does Snail play in cell migration?
Regulates EMT (epithelial to mesenchymal transition)
EMT is necessary for cells to become migratory.
Fill in the blank: Neural plate formation occurs during _______.
neurulation
True or False: The neural crest cells originate from the edges of the neural plate.
True
