Neuro Flashcards

(34 cards)

1
Q

What is the definition of homeostasis?

A

Dynamic constancy

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2
Q

What does negative feedback do?

A

An increase or decrease in a variable causes a response that moves variables in the opposite direction

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3
Q

What is positive feedback?

A

An accelerated, explosive system, and the feedback stops when the stimulus does

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4
Q

Birth, blood clotting, and sexual orgasm are examples of what type of feedback?

A

Positive

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5
Q

Responses to Na+ change, temperature change, and blood pressure changes are what type of feedback?

A

Negative

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6
Q

The stimulus strength affects spike height in action potentials or local potentials?

A

Local potentials

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7
Q

Stimulus strength affects frequency in action potentials or local potentials?

A

Action potential

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8
Q

What triggers local potentials?

A

Ligand binding

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9
Q

Which can sum, between action potentials and local potentials?

A

Local potentials

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10
Q

What causes voltage-gated ion channels to open?

A

Membrane depolarization

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11
Q

What opens the voltage gated Ca2+ channel of the presynaptic terminal?

A

The action potential and Na+ entry

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12
Q

What does calcium do in the pre-synaptic axon?

A

Helps synaptic vesicles fuse with the pre-synaptic membrane and release neurotransmitters

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13
Q

Which type of receptor is a receptor and a channel?

A

Ionotropic

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14
Q

Which receptor type is slow and longer lasting?

A

Metabotropic

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15
Q

What activates a metabotropic receptor?

A

Neutrotransmitter binds, activates g-proteins, g-proteins activate the receptor

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16
Q

What do G-proteins do?

A

Activate metabotropic receptors when stimulated by neurotransmitters

17
Q

What does cocaine inhibit the reuptake of?

18
Q

Which medication hyperpolarizes excited cells?

A

Anti-anxiety medication

19
Q

Which medication acts like GABA towards excited cells?

A

Anti-anxiety medication

20
Q

Which drug blocks the modulatory interneuron?

21
Q

Inhibitory or excitatory? NT binds to ionotropic receptor, chlorine flux. Chlorine high outside compared to inside

A

Inhibitory - negative ions coming in

22
Q

Excitatory or inhibitory? NT binds to metabotropic receptor, second messenger cascade closes a calcium channel

A

Inhibitory, loss of positive ion flux

23
Q

Calcium is high inside or outside cells?

A

Very high outside

24
Q

What is happening at rest at the sarcomere?

A

Tropomyosin is covering the myosin binding site on the actin

25
Where is the myosin binding site?
Actin
26
What causes tropomoysin to pull off the myosin binding site?
Calcium binds to troponin
27
Acetylcholine binds to what receptor on the muscle cell endplate?
Nicotinic receptor
28
What type of receptor is a nicotinic receptor?
Metabotropic
29
What does the nicotinic receptor do on the muscle cell endplate?
Opens channels, Na+ influx
30
The action potential propagates down the muscle cell membrane and hits what?
DHP membrane
31
How is the Ryanodine receptor opened?
DHP changes conformation, communicates with and opens the Ryanodine receptor
32
Where is calcium being held in the muscle cell?
Sarcoplasmic reticulum (SR)
33
How does calcium exit the SR?
Ryanodine receptor on the SR opens to allow calcium into the muscle cell cytoplasm
34
What is the calcium source for muscle excitation?
Extracellular