Neuro Flashcards

(32 cards)

1
Q

Multiple system atrophy triad

A

Cerebellar
Parkinson
Autonomic (ED)

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2
Q

Drug that causes acute angle closure glaucoma used in migraines

A

Topiramate

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3
Q

In Narcolepsy which neuropeptide is low

A

Orexin (hypocretin)

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4
Q
A
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5
Q

Apomorphine works on which receptors

A

Dopamine receptors

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6
Q

scale that measures disability or dependence in activities of daily living in stroke patients

A

The Barthel index

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7
Q

Measures the risk of developing pressure sore in a patient

A

Waterlow score

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8
Q

Assess the risk of malnutrition

A

MUST

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9
Q

In migraine analgesics may fail to relieve acute attack because

A

Delayed gastric emptying
Combined with pro kinetic drug like metocloperamide

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10
Q

5-HT2 antagonists and 5-HT3 antagonists …

A

HT3» ondansetron&raquo_space; antiemetic

HT2» resperidone/olanzapine&raquo_space; antipsychotic

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11
Q

MS treatment that carries highest risk of developing PML (progressive multifocal leukoencephalopathy)

A

Natalizumab» activation of JC virus

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12
Q

Miller fisher syndrome

A

Ophthalmoplegia (first)
Descending paralysis

Commonest trigger» C. jejuni infection

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13
Q

Downbeat nystagmus seen in

A

Arnold Chiari malformation

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14
Q

Upbeat nystagmus seen in

A

Cerebellar vermis

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15
Q

Drug induced parkinsonism

A

No tremor and rigidity

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16
Q

Ataxia telangiectasia

A

Cerebellar ataxia
IgA deficiency&raquo_space; recurrent chest infection
Telangiectasia

17
Q

Miller Fisher syndrome

A

Descending paralysis + ophthalmoplegia

Anti-GQ1b

18
Q

Opioid used in neuropathic pain

A

Tramadol:

Has both opioid action + serotonin and norepinephrine re uptake inhibition

19
Q

Na Valproate effect on hepatic enzymes

20
Q

Triptans mechanism of action

A

5-HT1(b&d) agonist

21
Q

Contraindications of triptans

A

History or risk of IHD or CVA

22
Q

Anti NMDA receptor encephalitis associated with

A

Ovarian teratoma

23
Q

Gingival hyperplasia causes

A

Phenytoin
Ciclosporin
CCB
AML

24
Q

Palatal myoclonus occur in

A

Hypertrophic olivary degeneration

25
First line for spasticity in MS
Baclofen and gabapentin
26
Anti parkinson drug that causes restrictive pulmonary disease
Pergolide
27
Baclofen works on which receptos
GABA B agonis
28
Seizure medication that causes drop in bp
Phenytoin
29
Anti epileptic drug stopping
Seizure free for >2 years Stopped over 2-3 months
30
Adverse effect rare and serious for lamotrigine
SJS
31
Most common characteristic symptom of CJD
Myoclonus
32
Typical feature of migraines
Phonophobia