neuro Flashcards

(89 cards)

1
Q

mini mental components

A

appearance, behavior, cognition, thought process

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2
Q

mini mental peumonic for 11 components

A

ORArL 2,3,RWD

Oreintatoin to place and time
Rrecognition0 repeat three objects (orange, dog and pencil)
Attnetion - serial 7s
recal - three objects from before 5 mins later
Language
2 names of 2 objects
3 three step commoand,
Read statment aloud, do what it says, dontsay it (close your eyes)
Write a sentance
Design- copy a design

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3
Q

mini mental pneumonic max score

A

max score is 30, no cog impariment is 24-30- average is 27

deleirum or dementia is 18-23 severe impairment is 0-7

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4
Q

TIA- deff

A

periods of acute cerebral insufficiency lasting less than 24 hours without residual effects

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5
Q

TIA causes

A

thrombus vs hemmorage,

cardio embolic event afib etc

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6
Q

TIA is indicative of

A

impending stroke

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7
Q

appro — % of pt wth TIA will experience a cerebral infarct in —-years

A

1/3 within 5 years

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8
Q

Tia class vertebrobasilar

A

innadequate blood flow from vertebral arteries

presentation is vertigo, ataxia, dizzy, visual field defficit, weakness, confusion

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9
Q

TIA class carotid

A

due to carotid stenosis,

presentation is aphasia, dysarthria, altered LOC, weakness, numbness etc.

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10
Q

TIA lab and DX

A

CT is best to distinguish between, tumor, bleed or ischemic stroke

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11
Q

TIA CT vs MRI

A

MRI is superior to CT in detecting ischemic infarcts.

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12
Q

TIA wk up after CT

A

echo, carotid doppler, cerepbral angioagraphy

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13
Q

TIA managemnt

A

asa reduces the risk of stroke and death

plavix 75mg QD

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14
Q

Tia problems with ticlid

A

agranulocytosis, thrombotic thrombocytopenia purpura, and gi intolerance

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15
Q

in TIA assess for hypertension as it is

A

nuber one cause of heart failure

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16
Q

tia and carotid endartoectmoy

A

decreases the risk of strok and death in patients with recent TIA, it is indicated for >70-80% stenosis of vessells for symptomatic patients..

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17
Q

CVA definition

A

rapid onset of neuro deficits lasting longer that 24 hrs (TIA is less than 24 hrs) it remains the 4th leading cause of death in the us

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18
Q

CVA causes

A

atherosclerotic changes, chronic hypertension, trauma, aneurysm, av malformation, tumor

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19
Q

CVA infarct pearl

A

can produce subtle, progressive or sudden neurologic deficits

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20
Q

CVA infarct signs and symptoms

A

change in loc
motor weakness
visual alterations
changes in vitals signs

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21
Q

CVA hemmorage pearl

A

usually presents with sudden onset focal neuro deficits

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22
Q

CVA hemmorhage S and S

A

signs associated with inreased ICP, emisis, altered mentation, HA,

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23
Q

CVA bleed Left dominent hemisphere

A

R hemiparesis, aphasia, dysarthia, difficulty reading or writing

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24
Q

CVA bleed R non dominant hemisphere,

A

left hemiparesis, right visual field changes, spatial disorientation.

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25
CVA labs and diagnostics
Head CT cerebral angiography LP if the pt has a grade I or II annurysm, to detect blood in CSF but CT should be first
26
CVA and LP contraindication
contra in large bleeds as brain stem herniation can be induced with rapid decompression of the subarachnoid space
27
more common infarct vs hemmorhage
infarct 80/20
28
thrombotic stroke management
fibrinolytic threapy indicated 3 is the answer up to -4.5 from last known well is contrverisal but done
29
stroke indications for ICP monitoring
sever head injury that cant allow for neuro assessment GCS <8 abnormal CT GCS
30
pipils changes are the
same
31
motor changes are
opposite
32
MAP and cerebral vasospasm
110-130 to prevent cerebral vasospasm.
33
door to fibrinolytic strok vs mi
3 vs 6 hrs
34
cpp formula
map-icp
35
nimitop role in cva
it si a calcium channel antagonist that helps to counter vasospasm by preventing calcium form entering the smooth muscle cells and causing contraction.
36
seizure classificaiton is based on
mode of seizure onset and spread
37
partial seizure | simple partial
(focal local) no LOC rarley greater than 1 minute motor symptoms start in one group and spread to entire side of body parastethisas, flashing lights, vocalizations, hallucinations common.
38
complex partial seizure
any simple seizure followed by impaired level of cociousness | may have aura, staring or automatisms such as lip smacking, and picking at clothing.
39
HHH that increase ICP
hypotension] hypercapnea hypoxia
40
generalized seizure absence (petite mal)
sudden arest of motor activity with blank stare | common discovered in children and adolescents begin and end suddenly
41
tonic clonic sx grand mal
may have aura begins with tonic - repititive contraction of muscles, loc then clonic contractions involantary contraction of muscles 2-5 mins incontinece my occure post ictal after.
42
grand mal seizures are commonly
discovered in children
43
status epileptics definition
series of grand mal seizures of >10mins in duration they are a medical emergency may occur when awake or asleep but pt never regains consciousness between episodes most uncommon but most life threatening seizure type
44
labs and diagnostics for seizures/assessment
presence of aura, onset, spread, type of movement, body parts involved,
45
seizures- eeg and CT
eeg is most important test in determining the seizure classifications CT is indicated for all new onset seizures
46
seizure management-
most are self limiting protect airway benzos- 2-4mg, at 1-2mg/min dilantin- 20mg/kg- at 50mg/in continuous phenobarb is dilantin fails
47
myasthenia gravis definition
autoimmune disorder resulting in the reduction of the number of acetycholine receptor sites at the neuromouscular junction
48
durg of choice to break status
valum
49
MG weakness
better at rest worst after activity | variable clinical course remission and execerbations
50
MG who gets it
20-40 but can happen at any age, younger for women men in the 50's and 60's more common in woman than man
51
MG s and s
PTOSIS DIPLOPIA disarthia, dysphagia, visual changes and extremity weakness
52
MG labs
``` antibody test (to acetycholine) tensilin test, edrophonium- if they get wores they had a cholinergic crisis, if they get better then its myasthenic crisis. ```
53
MG management
anticholinesterase drugs to block the hydrolosis of acetylcholine and are used for symptomatic improment- prostigmine. immunosuppressives plasmapharesis, vent
54
Multiple Sclerosis
autoimmune disease marked by numbness, weakness, loss of muscle coordination, and problems with VISION SPEECH AND BLADDER CONTROL immune system attackes nerve insulator variable clinical course
55
MS
young adults between 20-50 mostly western european descent living in temperate zones
56
MS symptoms MRi
``` weakness, numbness, tingling, or unsteadiness in a limb, may progress to all limbs spastic paraparesis diplopia, urinary symtoms, optic atrophy nystagmus ```
57
MS diag
MRI of brain, cant base diagnosis solely on labs, slight protien elevation in CSF IgG also elevated.
58
MS treatment
neuro refferal, steroids for acute relapses, antispasmodics, interferon therapy, plasmapharesis
59
GB definition
acute usually rapidly progressive form of inflammatory polyneuorpathy characterized by demylinaiton of the peripheral nerves resulting in SYMMERICAL ASCENDING PARALYSIS
60
GB causes
unknown, usually preceded by a suspected viral infection accompanied by fever, 1-3 weeks before the onset of acute bilateral muscle weakness in the lower extremities flaccid paralysis can result within 48-72 hours
61
GB incidence
male and female are equal,
62
GB S and S
typically a rapidly progressive paralysis with cranial nerve involvement. reflexes are hypoactive or absent
63
GB labs
CSF protein is usually elevated (especially Immunogloublin G
64
Meningitis definition
infection of the membranes of the pia matter and arachnoid matter of the brain or spinal cord
65
Meningitis pearls
should be considerd in any patient with fever adn neuro symptoms especially with history of other infection or head trauma acute bacterial meningitis is a medical emergency
66
meningitis bacteria
in 80-90% of the cases it is caused by Streptococcus pneumoniae, H influenze, or nisseriea meningitidis
67
meningitis symptoms
fever 101-103, severe headache, STIFF NECK, KERNIGS SIGN, pain and spasm of hamstring muscles, Brudzinski- legs flex at both the hips and the knees in response to the flexion of the head and neck to the chest, photophobia and seizures
68
meningitis dx
LP- CSF will be cloudy or xanthochromic (yellow) with elevated pressure, protein, decreased glucose, with WBC's CT of head is indicated
69
monroe kelly dosctrine,
when one pressure in head increases another must decrease.
70
meningitis tx
high does IV abx, Penicillin G, vanc with a thrid generation cephalosporin
71
cushings
bradycardia hypertention, slow or strange respiration
72
battles sign
brusing behind ears at mastoid process
73
labs for head injury
everyone gets c spine | ct head and skull films
74
Four p's of spina cord injuries
pain, position, aralysis, paresthesias
75
lucid interval is what type of hematoma
epidural
76
C and T
C injury = quad | T can move arms parapalegiea
77
spinal cord injury
methlprednisolone - 30mg/kg iv bolus followed by 5.4mg/kg infusion per hour for 24 hours withing the first 8 hours of injury
78
5 complications of spinal trauma
C4 or above equals respiratory compromise | T4-T6 may lead to autonomic dysreflexia- an emergency medical condition
79
autonomic dysrefleia-
exaggerated autonomic response, to a stimulus, bladder or bowel distention, hot or cold stim, restrictive clothing symptoms include, diaphoresis and flushing aboe the level of the injury chills and severe vasoconstriction below the level of the injury HTN Bradycardica Headache nausea tx is remove stim and BP control
80
brown sequard syndrome
caused by damage to one half of the spinal cord ipsilateral upper motor nuron paralysis and loss of propriaoception tx is MRI and steroids
81
cauda equina
compression of nerve roots at the end of the spinal cord numbness in lowerlegs, or saddle region, mri,steroids, surgery for decompresssion.
82
T6 or above-
neurogenic schock may occur disruption of sympathetic impulses causes uninterupted parasympthetic stim leading to massive vasodilation hypovolemia low bp pressors
83
parkinsons definition
not enough dopamne 45-65 all groups
84
parkinsons triad
TREMOR, BRADYKANESIA, AND RIGIDITY wooden faces, myersons sign- repetive tapping produces sustained blinking impaired swallowng
85
parkisons management
up dopaine carbidopa-levodopa- sinamet amantadine mirapex help with tremor cogentin, artane,
86
dementia causes
``` atheosclerosis, neurotransmitter deficits cortical atrophy ventricular dilation loss of brain cells possible viral causes alzheimers disease ```
87
Dementia pneumonic
``` drug reactions emotional disorders metabolic or endocrine disorders emotional disorders nutritional problems tumors infection ateriosclerosis ```
88
agnosia
cant recognize an object
89
most common alzheimenrrs drug
aracept