Neuro Oncology Flashcards Preview

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Flashcards in Neuro Oncology Deck (26):
1

MC brain tumors?

#1-mets
MC primary= astrocytomas

2

What are the three main types of astrocytomas?

-pilocytic
-anaplastic
-glioblastoma

3

Pilocytic astrocytoma:
-gross appearance
-microscopic appearance
-age group

-cystic, around ventricles vs cerebellum
-Rosenthal fibers (red worms)
-children or young adults

4

Which glioblastoma is most malignant?

-glioblastoma, shockingly, NOT anaplastic

5

Anaplastic astrocytoma:
-microscopic appearance
-life expectancy

-^^ cells, mitoses, abnormal nuclei
-less than five years

6

Glioblastoma:
-presentation
-age group
-survival rate

-seizures, focal deficit
-5th-7th decades
-survival 12-18 months

7

Glioblastoma:
-microscopic appearance
-gross appearance

-pseduopalisading necrosis
-butterfly (crosses corpus), ring enhancing

8

Oligodendrogliomas:
-presentation
-age group
-life expectancy

-seizures
-4th-5th decade
-5-10 years (can resect + chemo)

9

Oligodendrogliomas:
-location
-microscopic appearance

-supratentorial**
-fried egg appearance

10

Ependymomas:
-age group
-presentation

-children --> young adults
-headaches + vision changes especially in the morning

11

Ependymomas:
-microscopic appearance
-gross location

-perivascular pseudorosettes
-fourth ventricle vs spinal cord (can be supra OR infratentorial)

12

MC spinal cord glioma?

ependymoma

13

Primitive Neuroectodermal Tumors:
general appearance

small round blue cells
(blastomas)

14

MC intracranial PNET

medulloblastoma

15

Medulloblastoma:
-location
-complication
-age group

-cerebellum
-drop mets to spinal cord
-children

16

Medulloblastoma:
-survival rate
-microscopic appearance

-5 years
-homer-wright rosettes

17

Retinoblastoma:
-microscopic appearance

true rosettes

18

MC type pituitary tumor

-functional prolactinoma

19

Treatment for prolactinoma:

-bromocriptine
-transnasal resection

20

Meningiomas:
-source
-microscopic appearance
-gross appearance

-arachnoid cells (not CNS)
-psammoma bodies
-dural tail

21

Brain mets:
-appearance

-multiple small lesions, poorly circumscribed, often at gray white junction

22

What are the most common tumors that cause brain mets?

Lots of Bad Stuff Kills Glia
-Lung
-Breat
-Skin (melanoma)
-Kidney
-GI

23

What brain mets are most likely to hemorrhage?

-renal
-melanoma
-choriocarcinoma

24

True Rosette:
-appearance + assc tumor

-central lumen
-retinoblastoma

25

Homer-Wright Rosette:
-appearance
-assc tumor

-medulloblastoma
-cytoplasmic process in center

26

Perivascular Pseudorosette
-appearance
-assc tumor

-vessel at center
-ependymoma