Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Physical Therapy > Neurobiology test 2 definitions > Flashcards

Neurobiology test 2 definitions Flashcards

1
Q

Tolerance

A

How much dosage is needed to get the same effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Precursor

A

A substance from which another substance is formed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Sensitization

A

Same dose will have a augmented (more intense) effect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Agonist

A

Drug that will facilitate the post-synaptic effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Antagonist

A

Drug that will BLOCK the post-synaptic effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Margin of safety

A

The difference of the negative effects of the drug and the positive effects of the drug

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Drug-dose response curve

A

Shows the ratio of dosage of the drug compared to the neg/pos effects of the drug.

Space between the 2 curves is the margin of safety

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Ways to get drug into the body

A 
Injection 
Oral 
Anally 
Inhalation 
Sublingual 
Topically
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Areas of interest for psychopharmacology

A

The effects on the body
The active site for the drug
The pharmakinetics (how it enters, travels through and leaves the body)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Two ways drugs reach the brain in animal models

A

Intracerebral- Targets areas of the brain

Intracerebralven

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Two ways drugs reach the brain in animal models

A

Intracerebral- Targets areas of the brain

Intracerebralven

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Criteria to be a neurotransmitter

A

Located in presynaptic cell
Activated by Ca+
Subjected to inactivation (breakdown)
Has a receptor that accepts the ligand

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the 3 ways signals can transmit across neurons

A

Neuocrine Signaling
Paracrine signaling
Endocrine signaling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the 3 ways signals can transmit across neurons

A

Neuocrine Signaling
Paracrine signaling
Endocrine signaling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Three ways ACh is transmitted

A

Somatic- ACh delivered directly between muscle and spinal cord
Parasympathetic- Delivered to the synaptic junction and the NMJ
Sympathetic- Delivered to the synaptic junction (NE at NMJ)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Where is ACh produced in the body

A

Pons
Basil forebrand
Medial Septum
Candace/Putamen in basil ganglia

17
Q

What synthesizes ACh

A

Acetyl co-enzyme and choline

18
Q

What will break down ACh

A

acetylcholinesterase

19
Q

Where is norepinephrine found and where is it produced

A

Found in sympathetic nervous system

Produced is the locus coeruleus

20
Q

What cell makes norepinephrine and what secretes it

A

Made by adrenergic cells and secreted by varicosities

21
Q

What areas will transfer/release dopamine

A

Substantia Nigra

Ventral Tegmental Area

22
Q

What tracks release dopamine in the SN and how does the dopamine travel

A

The nigrostriatal track

From the SN to the Basal Ganglia

23
Q

What tracks release dopamine in the VTA and how does the dopamine travel

A

Mesolimbic - VTA to limbic system

Mesocortical- VTA to cortex

24
Q

What will block dopamine receptors on a cell

A

Cocaine

25
Q

What will deactivate catecholamine

A

Monoamines Oxidase

26
Q

What will deactivate serotonin

A

Monoamine Oxidase

27
Q

Where is serotonin released

A

Throughout the brain

28
Q

What cells have access to tryptophan

A

All cells

29
Q

Where is the serotonin produced

A

The Raphe nuclei

30
Q

What can Monoamines Oxidase break down

A

Dopamine
Norepinephrine
Epinephrine
Serotonin

31
Q

What can Monoamines Oxidase break down

A

Dopamine
Norepinephrine
Epinephrine
Serotonin

32
Q

What is the function of a neuropeptide

A

Regulates glucose level

33
Q

How can drugs effect neurotransmitters

A

How they are released
How they are synthesized
How they are packaged
How they are received

34
Q

What effect does Marijuana have on NT

A

Will effect dopamine downstream
Stimulates cannabinoid receptors
Very low toxicity so hard to overdose

35
Q

What are the effects of LSD

A

Will alter ones perceptions

Physical Therapy (18 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions