Neuroblastoma Flashcards
(7 cards)
1
Q
Most common EXTRA-CRANIAL tumor in childhood
A
Neuroblastoma
2
Q
Age of onset
A
Most cases before 5 years [average 2 years]
3
Q
Originate from
A
SNS
- 50% start in the Adrenal gland
4
Q
Clinical Features
A
- Abdominal mass crosses the midline
Raccoon Eyes + Periorbital proptosis [Bulging eye]
5
Q
Association with
A
Paraneoplastic syndrome:
1. Opsioclonus – myoclonus Ataxia Syndrome
Dancing Eyes + Dancing Feets
2. Horner Syndrome
* Secondary Hypertension
6
Q
Diagnosis
A
Bone Marrow Biopsy – Rosette Cells
Catecholamine metabolites increase in 24 h. urine test
[ HVA, VMA ]
CT/MRI
7
Q
A
