Neurodevelopment 1 Flashcards

1
Q

___% of births are without major neurodevelopmental dysfunction

A

97

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2
Q

about ___ the protein coding genes are also in some way involved in development of the NS

A

half

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3
Q

____: you are born with the attributes to survive on its own

A

precocious

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4
Q

most neuronal production and migration occurs during the ___ through ____ months of development

A

3rd-5th

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5
Q

the formation of neural connections and production of myelin sheaths continue ____ birth

A

after

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6
Q

____: neural connections

A

neuropil

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7
Q

___: where axons and dendrites meet

A

neuropil

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8
Q

gliogenesis takes place during the ___ and ___ trimesters of pregnancy and early ___ development

A

2nd and 3rd

postnatal

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9
Q

glia outnumber neurons __:___ in the fully developed brain

A

10:1

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10
Q

glial abnormalities related to….

A

alzheimers
MS
schizophrenia
depression

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11
Q

schizophrenia can be related to the mother getting sick during ____

A

pregnancy

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12
Q

when cells are in the morula they are ___

A

totipotent

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13
Q

___: cells have the potential to make its own organism itself

A

totipotent

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14
Q

when cells are in the blastocyst, they are ___

A

pluripotent

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15
Q

____: potential to make many things

A

pluripotent

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16
Q

___ is when cell differentiation begins

A

gastrulation

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17
Q

gastrulation is going from ___ to ___ cell layers

A

2 –> 3

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18
Q

3 germ layers after gastrulation

A

ectoderm
mesoderm
endoderm

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19
Q

ectoderm gives rise to ___ ___ and ___

A

NS

Skin

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20
Q

mesoderm gives rise to __ and ____

ALSO ___

A

skeleton
musculature
Notochord

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21
Q

endoderm gives rise to the __ ___

A

gut tube

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22
Q

neurons have to rely on ____

A

cues

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23
Q

neural induction follows gastrulation from ___ acting on ectoderm

A

morphogens

24
Q

___ ___: undifferentiated tissue becomes nervous tissue

A

neural induction

25
_____ provides neural inducing morphogens to the ectoderm
mesoderm
26
morphagens are ___ that send specific signals that will determine the fate of an undifferentiated tissue
cues
27
extra embryonic tissue contains ___
BMP
28
when BMP comes into contact with undifferentiated ectoderm it gets a morphogen to become ___
epidermis
29
notochord secretes an enzyme that ___ BMP
blocks
30
notochord becomes the ___ ____ in the adult
nucleus pulposus
31
___ is the process of forming the neural tube from ectoderm
neurulation
32
neurulation involves: - formation of the ___ ___ - neural plate becomes ___ ___ - groove becomes closed ___ ___
neural plate neural groove neural tube
33
___ ____ results from incomplete caudal neural tube closure
spina bifida
34
2 types of spina bifinida cystica
meningocele | meningomyelocele
35
spina bifida cystica meningocele
not covered and have a bump | still in line and can come out
36
spina bifida cystica meningomyelocle
more intense motor deficiencies offset spinal cord
37
___ results from incomplete rostral neural tube closure
anencephaly
38
the neural tube is the ___ ___ ___
CNS
39
3 vesicles develop into the future brain
presencephalon mesencephalon rhombencephalon
40
cervical flexure is between the ___ and ___
rhombencephalon | spinal cord
41
cephalic flexure is between the ___ and ____
mesencephalon | prosencephalon
42
rhombencephalon separates into the ___ and __ at level of pontine flexure
metaencephalon | myelencephalon
43
prosencephalon separates into the ___ and ___
diencephalon | telencephalon
44
telencephalon turns into 3 things
cerebral cortex corpus striatum/basal ganglia hippocampus
45
diencephalon turns into 3 things
thalamus hypothalamus retina
46
mesencephalon turns into the ___
midbrain
47
metencephalon turns into 2 things
cerebellum | pons
48
myelencephalon turns into the ___ ____
medulla oblongata
49
lumen of the neural tube becomes the ___ ___
ventricular system
50
each vesicle contains different ___
ventricle
51
choroid plexus is: ____ ___ + ____+___ ___
vascular tissue pia ependymal cells
52
ependymal cells make ___
CSF
53
a "c" shape emerges with cortical development around the ___
insula
54
shaped growth of the "c" shaped structures ____ structures that are beneath the ____
rotates | neocortex
55
4 structures that are c shaped
corpus callosum basal ganglia hippocampus choroid plexus