Neurodevelopment Flashcards

(36 cards)

1
Q

Meroancephaly

A
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2
Q

Anencephaly

A
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3
Q

Spina Bifida

A
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4
Q

Exencephaly

A
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5
Q

Folic Acid during pregnancy

A
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6
Q

Example of Segmentation

A
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7
Q

3 Primary and 5 Secondary Vesicles

A

Telencephalon, Diencephalon, Mesencephalon, Metencephalon, Myelencephalon

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8
Q

Otx2 role in anterior posterior neural structure. Disease caused by absence.

A
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9
Q

Wnt signaling role in rostral caudal

A
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10
Q

FGF 8 role in Anterio-posterio patterning.

Interaction of Pax6 and Emx2

A
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11
Q

Hox Gene function

A
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12
Q

Two inductive cues for dorsoventral axis

A
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13
Q

Holoprosencephaly

Disease and Cause

A
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14
Q

SHH Mechanism of patterning dorsal-ventral

A
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15
Q

Two mechanisms of cell differentiating

A
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16
Q

4 Major types of neural crest cell migratory pathways

17
Q

Chicken Quail study - Nueral Crest Cell Purpose

18
Q

Development of Cortical Layers - unique maturation

19
Q

Migration of inhibitory neurons

20
Q

Failure of GABAnergic neuron migration effect

21
Q

Lissencephaly - mutation that causes this

22
Q

Cause of double layering in neuronal migration

A

DcX Tubulin Mutation

23
Q

End anatomy of growing Neuron. - Two parts to this feature

24
Q

Long Range Cues for Guidance

25
Short Range Cues for Guidance
26
General Mechanism - axon guidance
27
Effect-Loss of robo-3 in Mauthner
28
Effect of robo-3 mutation in humans
29
Sperry Frog outcome - growing back to original places or new places
30
Attractants and Repellents in eye for axon guidance. Where is EphB expressed Where is EphrinA expressed
31
How does motor activity affect motor neuron formation
32
What are neurotrophins
33
Post-synaptic cell role in trophic factors
33
NGF role w sympathetic neurons
34
Neuron competition - effect Which neurons do best
The Largest and Earliest
35
Ventricles derived from