Neurologic disorders Flashcards

(69 cards)

1
Q

what is the CNS

A

brain and spinal cord

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2
Q

what is the PNS

A

peripheral nerves

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3
Q

what are glial cells

A

support cells
structure for neurons

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4
Q

assessment of neuro system

A

cognitive fx- remember words, dates, draw
facial droop- ask pt to smile, open up mouth
extremities- tremors, rigidity, lack of strength
motor strength- bilateral grip and quadriceps strength against resistance
DTR- babinski- should be neg
sensation- pt eyes closed

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5
Q

what is generalized onset seizure

A

whole brain

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6
Q

what is focal onset seizure

A

1 side of brain

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7
Q

what is clonic

A

rhythmic muscle twitching

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8
Q

what is atonic

A

go limp

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9
Q

what is myoclonis

A

nonrhythmic muscle twitching

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10
Q

what are absence seizures

A

staring spell
gone from presence

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11
Q

what is aura

A

sensation b4 seizure
smell, feeling, etc

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12
Q

what is ictal period

A

time of seizure
do not touch pt

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13
Q

what is postictal

A

after seizure
exhausted
confused

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14
Q

what is interictal

A

period btwn multiple seizures

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15
Q

what is status epilipticus

A

seizure lasting >5 min
medical emergency: can lead to permanent brain damage

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16
Q

what causes seizures

A

head trauma
stroke
brain neoplasms
congenital malformation
degenerative brain disorder
environmental stimuli
genetic predisposition
infections
metabolic disturbances: electrolye imbalance
perinatal injury
withdraw from alc or sedative-hypnotic drugs

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17
Q

what is epilepsy

A

chronic neurological disorder with recurrent seizures
2 unprovoked seizures at least 24 hrs apart

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18
Q

characterisitcs of migraine headaches

A

1 sided
periodic, throbbing headaches
altered perceptions, nausea, and severe pain
lasting 4-72 hrs
aggravated by routine physical activity
sensitivity to light and or sound

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19
Q

risk factors for migraines

A

female
oral contraceptive use
excessive exercise
stress/worry
fatigue/lack of sleep
foods with nitrites, aspartate, tyranmine
hypoglygemia

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20
Q

how to treat migraines

A

NSAIDs
serotonin receptor agonists
dopamine receptor antagonists
preventative, prophylactic treatment
botox

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21
Q

characteristics of tension type headaches

A

most common
bilateral pain with mild to moderate pressure
does not worsen with physical activity
no nausea and vomiting
increased cervical and pericrainial muscle activity
lasting from 30 min-7 days
sensitivity to either light or sound

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22
Q

treatment for TTH

A

pain relievers
relaxation therapy
SSRIs

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23
Q

what is MS

A

chronic demyelinating disorder
affects brain, spinal cord, and optic nerves
remissions and exacerbations
sensory and motor

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24
Q

symptoms of MS

A

weakness
numbness
balance probs
blurred vision
dysphagia
hemiparesis
paraparesis
memory probs

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25
what is guillain barre syndrome
t cell mediated d/t virus postinfectious disease: epstein barr, covid acute inflammatory demyelination
26
symptoms of guillain barre
weakness complete paralysis- starts @ feet- ascending- breathing peripheral neuropathy
27
treamtnet for GBS
supportive neuromuscular respiraotry failure- vent continuous hemodynamic monitoring- autonomic nerves involved immunomodulating agents
28
what is myasthenia gravis
autoimmune chronic fights acetylcholine muscle weakness and fatigue extraocular muscles affected first b and t cell mediated thymus gland hyperplasia- overproduces t cells
29
diagnostics tests for MG
edrophonium testing serum ach receptor antibodies EMG
30
treatments for MG
physostigmine iv immunogobulin plasmapharesis thymectomy
31
what is myasthenic crisis
weakness severe enough to cause respiratory failure necessition vent requires ICU monitoring of forced vital capacity and neg inspiratory force every 2-4 hrs
32
what is obtunded
difficult to arouse
33
what is normal ICP
5-15 mm/hg
34
3 elements of ICP
brain tissue blood volume/circulation CSF
35
how to decrease pressure
drain fluid decrease bp hypertonic vasoconstrict remove brain tissue remove part of skull (decompressive crainiotomy)
36
what oercentage is brain tissue
80
37
what percentage is CSF
10
38
what percentage is blood
10
39
what can caused increased icp
mass tumor trauma bleed ischemic stroke hydrocephalus airway obstruction hypoventilation seizures
40
what is the monroe-kellie hypothesis
one of above volumes compensates for the other that rises once the need for volume can not be compensated for, ICP rises
41
assessment of TBI
head trauma neuro exam durations of unconsciousness post-traumatic amnesia consciousness vs unconsciousness cranial nerve testing both sides- pupil reaction to light, extraocular movements, corneal reflex, hearing, uvula and tongue position sensory testing- light touch, pain, positioning motor testing DTR coordination and gait mental status glascow coma scale coma and posturing
42
what does the glascow coma scale assess
severity of brain injury eye opening, verbal response, motor response lowest: 3 highest: 15- conscious
43
what is decoritacte
flexed arms, clenched fists, rigid legs indicates corticospinal tract damage
44
what is decerebate
arms held striaght outward with toes pointed downward indicates upper brainstem damage
45
what is post concussion syndrome
may persist for several months
46
treatment of mild tbi
certain activities should be resitrcted frequent rest stop playing sport/activity immediately until assessment and cleared by clinician to return to activity
47
treatment of modereate to severe tbi
intensive care unit
48
what is diffuse axonal injury
common type of tbi widespread damage to brain tissue major cause of unconsciousness and persistent coma after head trauma immediate loss of consciousness, most remain in coma
49
treatment for DAI
neurovascular stabilization IV mannitol, steroids
50
what is a concussion
mild TBI traumatic force causes disruption in brain fx
51
what is a simple concussion
resolve without complication may take up to 10 days
52
what is a complex concussion
symtoms may persist for longer longer loss of consciousness
53
what may a pt state after a concussion
seeing stars dazed confused headache dizzy retrograde and antegrade amnesia
54
diagnosis for concussion
rule out cervical spine injury, epidural hematoma, subdural hematoma, subarachnoid hemorrhage neuro exam s&s may evolve over time so do repeat evals ct scan normal in most cases
55
what is post-concussion syndrome
persistence of symptoms for more than 3 weks
56
what is a cerebral contusion
scattered areas of bleeding on brain surface most commonly undersurface frontal and temporal lobes cerebral edema around contusion within 48-72 hrs medical emergency- decreased HR, decreased respirations, hypertension, can not be awakened
57
treatment for cerebral contusion
crainectomy/crainotomy evacuation of blood through crainiotomy
58
what is intracranial bleeding
epidural and subdural hematoma can cause excessive pressure on brain and cause neuro damage or death
59
what is epidural hematoma
collection of arterial blood above dura mater that is caused by rupture of the middle meningeal artery commonly associated with skull fracture
60
what is a subdural hematoma
collection of venous blood that is beneath dura mater
61
what is a spinal cord injury
compression, stretching, or laceration of spinal cord d/t trauma can result in impaired blood flow causes temp or permanent sensory, motor or autonomic fx that are seen immediately after injury deficits can worsen over time r/t edema quadriplegia is most common type: all 4 limbs paraplegia is second most common type
62
where is a complete SCI
c4 or above
63
where is an incomplete SCI
t11 or below
64
what is a primary sci
mechanical- stretching or shearing forces injure neurons and glial cells hemorrhage, cell death, and necrotic enviornment
65
what is a secondary sci
ischemia caused by primary forces causes secondary injury processes that worsen damage over hours to weeks ischemia cause cytotoxic edema, inflammation, cascade of tissue damage and scarring which inhibits regeneration of neurons at side of injury
66
assessment for sci
abc's log roll- treat all back injuries as if they have sci until confirmed they do not pulmonary -injuries at c4 and above tend to have respiratory complications look for signs of hemorrhage, hypotension and shock sensory testing motor strength testing extent of injury
67
treatment for sci
ABCs stabilization neuro exam pain management SCDs-immobile wound care urinary cath warmed IVF surgery LMW heparin if no bleeding risk
68
what is spinal shock
areflexia: absence of reflexes results from primary injury flaccid muscles, paralysis, lack of sensation below injury, bowel and bladder dysfunction loss of anal reflex or bulbocavernosus reflex autonomic fx also disrupted cannot assess extent of injury until shock resolves, may take weeks to days indicated by return of anal reflex
69
what is neurogenic shock
acute occurs in pt's with injuries at t6 and above autonomic probs abnormal SNS signaling bradycardia hypotension peripheral vasodilation hemodynamic monitoring and stabilization required- fluids