Neurophysiology part 1 stack 3 Flashcards

(43 cards)

1
Q

Repolarization in generating an AP resets ____, not ionic conditions?

A

electrical conditions

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2
Q

What occurs after repolarization in generating an action potential?

A

Na+/k+ pumps restore ionic conditions

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3
Q

How are the concentrations of Na+ and K+ different on each side of the membrane after repolarization?

A

Na+ concentration is higher outside cell, K+ concentration is higher inside cell

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4
Q

True or false: not all depolarization events produce APS

A

True

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5
Q

What must occur for an axon to “fire”?

A

depolarization must reach threshold voltage to trigger AP

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6
Q

What 4 conditions are involved at threshold that must be reached for axon to fire?

A
  • Membrane is depolarized by 15 to 20 mV
  • Na+ permeability increases
    -Na+ influx exceeds K+ efflux
  • The + feedback cycle begins
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7
Q

What is the definition of All-or-None?

A

When an AP either happens completely or does not happen at all

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8
Q

What does propagation allow an AP to do?

A

to be transmitted from origin down entire axon length toward terminals

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9
Q

Na+ influx through voltage gates in one membrane area cause___?

A

local currents that cause opening of Na+ voltage gates in adjacent membrane areas, leading to depolarization of area and to next as a result

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10
Q

an AP is self propagating ___?

A

once propagation is initiated

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11
Q

What happens in nonmyelinated axons in propagation?

A

each successive segment of membrane depolarizes then repolarizes

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12
Q

What differs in myelinated axons?

A

Propagation

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13
Q

Why is no new AP generated in AP origin?

A

due to Na+ channels closer to AP origin being inactivated

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14
Q

What direction do APs occur?

A

only in a forward direction

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15
Q

All APs are __ and are independent of what ?

A

alike, stimulus intensity

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16
Q

How can CNS tell difference between a weak stimulus and a strong one?

A

by the frequency of impulses

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17
Q

What is frequency regarding APs?

A

the number of impulses received per second (impulse/second)

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18
Q

Higher frequency in AP mean ?

A

stronger stimulus

19
Q

Time in which neuron cannot trigger another AP is know as?

A

refractory period where voltage gated Na+ channels ar open, preventing neuron from responding to another stimulus

20
Q

What are the two types of refractory period?

A

absolute refractory period and relative refractory period

21
Q

Absolute refractory period is the time from what to what?

A

opening of Na+ channels until resetting of the channels

22
Q

What does absolute refractory period ensure?

A

that each AP is an all-or-none event

23
Q

Absolute refractory period enforce ___?

A

one way transmission of nerve impulses

24
Q

What are Na+ channels and K+ channels like in relative refractory period?

A

Most Na+ channels have returned to their resting state and some K+ channels still reopen

25
Relative refractory period follow refractory period, true or false?
True
26
Repolarization is occurring in relative refractory period, true or false?
True
27
What state is the threshold in relative refractory period?
threshold for AP generation is elevated
28
What could stimulate an AP in relative refractory periods?
only exceptionally strong stimulus
29
30
Review: where do APs occur in?
only in axons
31
AP conduction velocities in axons vary widely, true or false?
true
32
What two factors doe rate of AP propagation depend on?
axon diameter; large diameter fibers have less resistance to local current flow so have faster impulse condition and degree of myelination
33
What are the two types of conduction depending on presence of absence of myelin in conducting velocity?
continuous velocity and saltatory conduction
34
What are continuous conduction like?
slow and occurs in nonmyelinated axons
35
What are saltatory conduction like?
are about 30 times faster than continuous conduction and occurs in myelinated axons
36
What is the role of myelin sheaths in saltatory conduction?
insulate and prevent leakage of charge
37
___ channels are located at myelin sheath gaps in saltatory conduction?
voltage-gated Na+
38
APs are generated in what location is saltatory conduction?
sheath gaps and electrical signals jump rapidly from gap to gap
39
What factors are never fibers classified on?
diameter, degree of myelination, and speed of conduction
40
What are group A nerve fibers ?
are the largest diameter and include myelinated somatic sensory and motor fibers of skin, skeletal muscles, and joints
41
What nerve fibers are intermediate in diameter and involve lightly myelinated fibers?
Group B
42
Group C fiber are ___ diameter and ___?
smallest, unmyelinated
43
What two group of nerve fibers include ANS visceral motor and sensory fibers that serve visceral organs?
group B and C nerve fibers