Neurophysiology part 1 stack 3 Flashcards
(43 cards)
Repolarization in generating an AP resets ____, not ionic conditions?
electrical conditions
What occurs after repolarization in generating an action potential?
Na+/k+ pumps restore ionic conditions
How are the concentrations of Na+ and K+ different on each side of the membrane after repolarization?
Na+ concentration is higher outside cell, K+ concentration is higher inside cell
True or false: not all depolarization events produce APS
True
What must occur for an axon to “fire”?
depolarization must reach threshold voltage to trigger AP
What 4 conditions are involved at threshold that must be reached for axon to fire?
- Membrane is depolarized by 15 to 20 mV
- Na+ permeability increases
-Na+ influx exceeds K+ efflux - The + feedback cycle begins
What is the definition of All-or-None?
When an AP either happens completely or does not happen at all
What does propagation allow an AP to do?
to be transmitted from origin down entire axon length toward terminals
Na+ influx through voltage gates in one membrane area cause___?
local currents that cause opening of Na+ voltage gates in adjacent membrane areas, leading to depolarization of area and to next as a result
an AP is self propagating ___?
once propagation is initiated
What happens in nonmyelinated axons in propagation?
each successive segment of membrane depolarizes then repolarizes
What differs in myelinated axons?
Propagation
Why is no new AP generated in AP origin?
due to Na+ channels closer to AP origin being inactivated
What direction do APs occur?
only in a forward direction
All APs are __ and are independent of what ?
alike, stimulus intensity
How can CNS tell difference between a weak stimulus and a strong one?
by the frequency of impulses
What is frequency regarding APs?
the number of impulses received per second (impulse/second)
Higher frequency in AP mean ?
stronger stimulus
Time in which neuron cannot trigger another AP is know as?
refractory period where voltage gated Na+ channels ar open, preventing neuron from responding to another stimulus
What are the two types of refractory period?
absolute refractory period and relative refractory period
Absolute refractory period is the time from what to what?
opening of Na+ channels until resetting of the channels
What does absolute refractory period ensure?
that each AP is an all-or-none event
Absolute refractory period enforce ___?
one way transmission of nerve impulses
What are Na+ channels and K+ channels like in relative refractory period?
Most Na+ channels have returned to their resting state and some K+ channels still reopen