Neurotransmission & ANS Pharmacology II: Cholinergic & Adrenergic Pharmacology

Question 1

What is an example of a Muscarinic Receptor Agonist?

Answer 1

Pilocarpine

Question 2

What is an example of a Muscarinic Receptor Antagonist?

Answer 2

Atropine

Question 3

What is an example of a Stimulating Ganglionic Drug?

Answer 3

Nicotine

Question 4

What is an example of a Blocking Ganglionic Drug?

Answer 4

Botulinum Toxin

Question 5

Which TWO types of Cholinergic agonists are Receptor Agonists?

Answer 5

1. Choline Esters (ACh, Bethanechol)
2. Alkaloids (Pilocarpine)

Question 6

Which TWO types of Cholinergic agonists are Cholinesterase Inhibitors?

Answer 6

1. Carbamates (Physostigmine, Neostigmine)
2. Phosphates (Isofluorophate)

Question 7

What type of Antagonist is Atropine?

Answer 7

Muscarinic Antagonist

Question 8

Which receptors do most Nicotinic Agonists stimulate?

Answer 8

Ganglionic and Motor Endplate receptors

Question 9

What is a drug that acts on the Autonomic Ganglia?

Answer 9

Botulinum Toxin

Question 10

What neurotransmitter does a drug have to interfere with to be considered ganglion blocking?

Answer 10

ACh

Question 11

What do Non-Polarising Neuromuscular blocking drugs do?

Answer 11

Block ACh receptors

Question 12

What do Non-Polarising Neuromuscular blocking drugs do?

Answer 12

Agonist at ACh receptors

Question 13

What drugs are competitive antagonist of ACh at Nm in skeletal muscle?

Answer 13

Tubocurarine Analogues

Question 14

What drug is an example of a Depolarising Agent (ACh analogue)?

Answer 14

Suxamethonium

Question 15

Which TWO AChE Inhibitor drugs are used in treating Alzheimer’s?

Answer 15

1. Doneprezil
2. Tacrine