Neurotransmitters Flashcards
(30 cards)
What does Serotonin regulate?
Mood, anxiety and sleep
What are the serotonin receptor types?
19 subtypes - ALL GPCR except 1
Are the serotonin receptors inhibitory or excitatory?
Both! - Depends on the receptor
What does Acetylcholine regulate?
Learning and memory, attention, and muscle movement
What are the types of Acetylcholine receptors?
Nicotinic and Muscarinic
What are the characteristics of the nicotinic ACh receptors?
Ionotropic and EXCITATORY
What are ALL the dopamine receptors?
D1-D5
What are the characteristics of the muscarinic ACh receptors?
GPCR’s - Inhibitory and Excitatory
Where do the D1 and D5 receptors function?
Ventral Tegmental Area
What do the D1 and D5 receptors regulate?
Reward, emotion, reinforcement, and addiction
Are D1 and D5 receptors excitatory or inhibitory?
Both! - Stimulates cAMP production
Where does D2-D4 receptors function?
Substantia Nigra
What do the D2-D4 receptors regulate?
Motor Control
What happens if the D2-D4 receptors die?
Development of Parkinson’s
Are D2-D4 receptor inhibitory or excitatory?
Inhibitory - Inhibits cAMP production
What do Norepinephrine receptors regulate?
Emotional arousal, mood, sexual behavior, and learning/memory
What are the 4 NE receptor subtypes?
a1, a2, b1, and b2
What are the characteristics of a1 NE receptors?
Excitatory - Activates Phosphorylase
What are the characteristics of a a2 NE receptor?
Inhibitory - Inhibits cAMP production / often an auto receptor
What are the characteristics of b1 and b2 NE receptors?
Excitatory - Stimulates cAMP production
What are the GABA receptors?
GABA A and GABA B
What are the characteristics of GABA A receptors?
Ionotropic - Chloride channels - INHIBITORY
What are the characteristics of GABA B receptors?
Metabotropic - INHIBITORY
GABA receptors are always…
Inhibitory
