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Flashcards in Neurotransmitters Deck (43):
0

Acetylcholine is secreted where

Nucleus Basalis of Meynert (mACH- meynert, muscarinic)

1

Synthesis of Ach uses

Acetyl Coa and choline

2

Enzyme that degrades Ach

Acetylcholinesterase

3

Associated with ach deficiency

Alzheimer's

4

Dopamin is found where

Substantia nigra para compacta and ventral tegmental area (dope)

5

Dopamine is degraded by

MAOI and COMT

6

Where is serotonin produced

Median raphe

7

Wc catecholamine has stronger B2 effect

Epinephrine

8

Where is NE produced

ILOCUS NORte (Locus ceruleus, NORepinephrine)

9

Inhibitor of pain pathway

Serotonin (sero pain)

10

Happy hormone

Serotonin

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Where is serotonin converted to melatonin

Pineal gland

12

Resting membrane potential is caused by

Nernst potential for Na and K diffusion, Na-K leak channels, Na-K-ATPase pump

13

What is Threshold

When Na influx > K leak/Efflux

14

Undershoot is caused by

Prolonged opening of K channels

15

Where do you get tetradotoxin

Puffer fish

16

Where do you get saxitoxin

Mussels (dinoflagellates)

17

Example of potassium channel blocker

Tetraethylammoniun (puffer fish)

18

Ionic basis for absolute refractory period

Closure of Na inactivation gates

19

Ionic basis for relative refractory period

Prolonged opening of K channels (POK- eR (relative))

20

When a cell is depolarized so SLOWLY such that the theshold potential is passed without firing an action potential

Accomodation

21

Where is ADH secreted

Supraoptic nuclei of the hypothalamus

22

ADH responds to ECF changes detected by osmoreceptors found where

Organum vasculosum (OrgasOSM)

23

Where is oxytocin produced

Paraventricular nuclei of hypothalamus

24

Most comon causr of elderly dementia

Alzheimer's

25

Dopamine deficiency leads to

Parkinsons

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Dopamine excess leads to

Schizophrenia

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Long term behavior and memory

Nitric oxide

28

Nitric oxide is from?

ArgiNIne (argentiNO)

29

Histamine is from

Histidine

30

Histamine is located where

Tuberomamillary nucleus of the hypothalamus

31

Involved in control of arousal, sleedp and circadian rhythm

Histamine

32

GlycINE is flound where

Spinal interneurons (glyc+ (sp)INE= glycINE)

33

Function of glycine

Increases chloride influx(inhibitory)

34

Number 1 inhibitory neurotransmitter in the brain

GABA

35

GABA is derived from

Glutamate

36

Function of GABA

A- chloride influx ; B- potassium efflux

37

Excitatory NT in brain

Glutamate

38

Inhibit neurons in the brain, involved in perception of pain

Enkephaljn, endorphin, dynorphin

39

Pain transmission

Substance P (substance pain)

40

Potential difference that exist across the membrane

Resting membrane potential

41

Typical resting membrane potential value

-70mV

42

Time periods in an action potential during wc new stimulus cannot be readily elicited

Refractory period