Neurotransmitters Flashcards

(43 cards)

0
Q

Synthesis of Ach uses

A

Acetyl Coa and choline

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1
Q

Acetylcholine is secreted where

A

Nucleus Basalis of Meynert (mACH- meynert, muscarinic)

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2
Q

Enzyme that degrades Ach

A

Acetylcholinesterase

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3
Q

Associated with ach deficiency

A

Alzheimer’s

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4
Q

Dopamin is found where

A

Substantia nigra para compacta and ventral tegmental area (dope)

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5
Q

Dopamine is degraded by

A

MAOI and COMT

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6
Q

Where is serotonin produced

A

Median raphe

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7
Q

Wc catecholamine has stronger B2 effect

A

Epinephrine

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8
Q

Where is NE produced

A

ILOCUS NORte (Locus ceruleus, NORepinephrine)

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9
Q

Inhibitor of pain pathway

A

Serotonin (sero pain)

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10
Q

Happy hormone

A

Serotonin

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11
Q

Where is serotonin converted to melatonin

A

Pineal gland

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12
Q

Resting membrane potential is caused by

A

Nernst potential for Na and K diffusion, Na-K leak channels, Na-K-ATPase pump

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13
Q

What is Threshold

A

When Na influx > K leak/Efflux

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14
Q

Undershoot is caused by

A

Prolonged opening of K channels

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15
Q

Where do you get tetradotoxin

A

Puffer fish

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16
Q

Where do you get saxitoxin

A

Mussels (dinoflagellates)

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17
Q

Example of potassium channel blocker

A

Tetraethylammoniun (puffer fish)

18
Q

Ionic basis for absolute refractory period

A

Closure of Na inactivation gates

19
Q

Ionic basis for relative refractory period

A

Prolonged opening of K channels (POK- eR (relative))

20
Q

When a cell is depolarized so SLOWLY such that the theshold potential is passed without firing an action potential

21
Q

Where is ADH secreted

A

Supraoptic nuclei of the hypothalamus

22
Q

ADH responds to ECF changes detected by osmoreceptors found where

A

Organum vasculosum (OrgasOSM)

23
Q

Where is oxytocin produced

A

Paraventricular nuclei of hypothalamus

24
Most comon causr of elderly dementia
Alzheimer's
25
Dopamine deficiency leads to
Parkinsons
26
Dopamine excess leads to
Schizophrenia
27
Long term behavior and memory
Nitric oxide
28
Nitric oxide is from?
ArgiNIne (argentiNO)
29
Histamine is from
Histidine
30
Histamine is located where
Tuberomamillary nucleus of the hypothalamus
31
Involved in control of arousal, sleedp and circadian rhythm
Histamine
32
GlycINE is flound where
Spinal interneurons (glyc+ (sp)INE= glycINE)
33
Function of glycine
Increases chloride influx(inhibitory)
34
Number 1 inhibitory neurotransmitter in the brain
GABA
35
GABA is derived from
Glutamate
36
Function of GABA
A- chloride influx ; B- potassium efflux
37
Excitatory NT in brain
Glutamate
38
Inhibit neurons in the brain, involved in perception of pain
Enkephaljn, endorphin, dynorphin
39
Pain transmission
Substance P (substance pain)
40
Potential difference that exist across the membrane
Resting membrane potential
41
Typical resting membrane potential value
-70mV
42
Time periods in an action potential during wc new stimulus cannot be readily elicited
Refractory period