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Nikcevich: Breast Cancer Therapy Flashcards

(20 cards)

1
Q

mammogram shows 2 cm spiculated lesion in UOQ.

what’s the next step?

A

biopsy

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2
Q

sentinel LN bopsy

A

if sentinel LN is negative, all the rest are negative

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3
Q

*ER + breast cancer: good news?

bad news?

A

no chemo necessary (tamoxifen for 5 years)

recurrence at year 11

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4
Q

*triple negative
bad news?
good news?

A
tx w/ chemo
NO recurrence (if get past year 3)
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5
Q

matalgia

A

breast pain

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6
Q

differential dx to rule out w/ mastitis?

A

inflammatory breast cancer

can be inflamed like mastitis

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7
Q

Mammogram shows a vague density. Next step?

A

MRI–WHEN IN DOUBT!

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8
Q

**cancer that is often SILENT on mammogram

A

lobular carcinoma

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9
Q

HER2NEU therapy?**

A
  • aromatase inhibitors (Post-MW)–> work on peripheral production (NOT for pre-MW)
  • tamoxifen
  • chemo
  • trastuzumab
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10
Q

tx for metastatic breast ca in setting of visceral crisis/rapidly progressing disease

A

chemo

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11
Q

*ER+/her2- breast cancer

A

hormonal therapy will add greatest benefit!

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12
Q

goals of tx metastatic breast cancer

A

paliate
prolong survival
improve quality of life

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13
Q

steps to evaluate/treat breast cancer

A

PE
mammogram (can also do on men)
biopsy
lumpectomy/masectomy

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14
Q

what should you consider in men w/ breast cancer?

A

BRCA gene testing

also test first degree relatives

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15
Q

edema that persists after mastitis

A

peau d’orange

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16
Q

routine mammogram recommended for

17
Q

breast cancer risk in the US

18
Q

95% of breast cancer in women occurs in what age group?

A

> 40

68% greater than 65

19
Q

risk reduction for women at risk for breast cancer

A

annual screening
tamoxifen
prophylactic masectomy

20
Q

model used to measure BC risk