Nikcevich: Breast Cancer Therapy Flashcards
(20 cards)
mammogram shows 2 cm spiculated lesion in UOQ.
what’s the next step?
biopsy
sentinel LN bopsy
if sentinel LN is negative, all the rest are negative
*ER + breast cancer: good news?
bad news?
no chemo necessary (tamoxifen for 5 years)
recurrence at year 11
*triple negative
bad news?
good news?
tx w/ chemo NO recurrence (if get past year 3)
matalgia
breast pain
differential dx to rule out w/ mastitis?
inflammatory breast cancer
can be inflamed like mastitis
Mammogram shows a vague density. Next step?
MRI–WHEN IN DOUBT!
**cancer that is often SILENT on mammogram
lobular carcinoma
HER2NEU therapy?**
- aromatase inhibitors (Post-MW)–> work on peripheral production (NOT for pre-MW)
- tamoxifen
- chemo
- trastuzumab
tx for metastatic breast ca in setting of visceral crisis/rapidly progressing disease
chemo
*ER+/her2- breast cancer
hormonal therapy will add greatest benefit!
goals of tx metastatic breast cancer
paliate
prolong survival
improve quality of life
steps to evaluate/treat breast cancer
PE
mammogram (can also do on men)
biopsy
lumpectomy/masectomy
what should you consider in men w/ breast cancer?
BRCA gene testing
also test first degree relatives
edema that persists after mastitis
peau d’orange
routine mammogram recommended for
50-74
breast cancer risk in the US
12%
95% of breast cancer in women occurs in what age group?
> 40
68% greater than 65
risk reduction for women at risk for breast cancer
annual screening
tamoxifen
prophylactic masectomy
model used to measure BC risk
gail model
