Non-specific diseases Flashcards

1
Q

What are non-specific defences?

A

these responses are exactly the same no matter what type of species of the invading pathogens

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2
Q

What are specific defences?

A
  • these responses produce antibodies and cytotoxic cells specific to invading pathogens
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3
Q

How does the skin act as an non-specific defence?

A
  • Flora of healthy microorganisms that out compete pathogens for space
  • sebum (oils) - inhibits growth of pathogens
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4
Q

How does the mucous membranes act as an non-specific defence?

A
  • Body tracts e.g air ways in the vagina lined by the mucus membranes
  • mucus traps microorganisms
  • lysosomes destroy pathogen cell walls
  • phagocytes engulfs pathogens
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5
Q

How does the inflammatory response act as an non-specific defence?

A
  • It is a localised response resulting to the inflammation at the site of a wound.
  • Characterised by pain, heat
  • mass cells are activated in damaged tissue and releases chemicals
  • Histamines make blood vessels dilate, causing heat and redness which prevents pathogens from entering.
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6
Q

How does blood clotting and wound repair act as an non-specific defence?

A
  • plateletes become sticky
  • they block hole/wound
  • Fibrin fibres clump the plateles and trap red blood cells together
  • thromboplastin - an enzyme that triggers a Cascades of reactions resulting in the formation of a blood clot
  • serotonin - makes smooth muscles in the walls of the blood vessels and contract so they narrow and reduce the supply to the blood area.
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