NSAIDs Flashcards

1
Q

Ketorolac: Class

A

NSAID
-nonselective COX 1 and 2 inhibitor

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2
Q

Ketorolac: Use

A

Pain relief
Antiinflammatory

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3
Q

Ketorolac: Mechanism of Action

A

Inhibition of prostaglandin synthesis by competitive blocking of the enzyme cyclooxygenase (COX 1 & 2)

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4
Q

Ketorolac: Dose

A

15 mg IV

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5
Q

Ketorolac: Pharmacokinetics

A

Absorption: PO, IV, IM

Onset: 30 minutes
Duration of Action: 4 hours

Metabolism: Hepatic

Excretion: Renal

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6
Q

Ketorolac: Contraindications

A

Decreased bone healing in Ortho cases
Bleeding Risk with inter cranial surgery

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7
Q

Ketorolac: Considerations

A

Can cause bronchoconstriction with asthma
Dose decreased in elderly and CKD
Give during emergence

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