Nucleic acids and Flow of Genetic Information (Lesson 5) Flashcards
(15 cards)
Nucleic Acids
Store and Transmit hereditary information in genes (units of inheritance), program AA sequence of the polypeptide (proteins)
Structure of Nucleic Acids
Made of nucleotides (monomers) -> link to form polynucleotides
1) Phosphate molecule (P)
2) 5-carbon sugar (S)
3) Nitrogenous base (F)
Deoxyribonucleic Acid (DNA)
Acts as a blueprint to make various proteins in our cells. A gene is a segment of DNA that encodes protein.
Function of DNA
- Needed for cell replication
- Contains genes
- Gense influence cells for which proteins make
- Complementary base pairing
Ribunucleic Acid (RNA)
Act as messengers to relay information (link between DNA/protein). Consist of a single strand of nucleotides.
Types of RNA involved in protein synthesis
1) mRNA 2)tRNA 3) rRNA
Difference DNA vs RNA (Strcture)
- DNA missing 1 oxygene from sugar (comparison)
- Thymine (T) –> Uracil (U)
- Double stranded –> Single Stranded
Genetic Information
Each gene carries information (blueprint) needed to make specefic protein + determines the primary sequence of protein. RNA allows it to leave nucleus
Transcription
Transfer of genetic information from DNA messenger RNA (mRNA)
- Seperation mRNA
- Synthesis mRNA (complementary to the DNA with base pair rule), make 1 copy of gene
Messenger RNA (mRNA)
DNA is like instructions so you must copy it/keep original
- single-stranded
- synthezised in nucleus with help enzymes/DNA
- information for 1 gene
- “words” organized in “codons” -> groups of 3 nucleotides that indicate a given AA
How many start/stop condone?
There is 1 start codone (AUG, methionine) and 3 stop codons
Translation
Assembly of the protein (primary structure) according to the mRNA
Codons
Provide sequence that AA must be arranged (create primary sequence)
Transfer RNA (tRNA)
tRNA communicates between mRNA and AA, each mRNA codone has an tRNA anticodone.
- Each has: 1) a unique codon
2) each tRNA can attach to only 1 kinf of AA
Ribosomes
Their structure makes them specialized bringing mRNA/tRNA together to make proteins.
Each contains 3 tRNA binding:
1) A site 2) P site 3) E site