Nucleotides and Nucleic acids Flashcards

1
Q

What three components make up a nucleotide?

A

A phosphate group, a pentose sugar and a base

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2
Q

Draw the basic nucleotide structure

A

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3
Q

What is the pentose sugar in DNA

A

Deoxyribose

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4
Q

Name the 4 bases in DNA and what 2 pairs they are in

A

Adenine and Thymine

Cytosine and Guanine

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5
Q

What is the change in the four bases in RNA

A

Thymine is replaced by Uracil

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6
Q

What is the basic structure of purine?

A

2 carbon rings

adenine and gyanine

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7
Q

What is the basic structure of a pyrimidine?

A

1 carbon ring

cytosine, thymine and uracil

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8
Q

What structure does ADP have?

A

Base adenine
Ribose sugar
Two phosphate groups

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9
Q

What structure does ATP have?

A

Base adenine
Ribose sugar
Three phosphate groups

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10
Q

What is it called when nucleotides join together and what bond is formed?

A

Polynucleotides

Phosphodiester bond

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11
Q

What is DNA composed of?

A

Two polynucleotide strands forming a double helix

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12
Q

How many bonds are formed between C and G?

A

3

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13
Q

How many bonds are formed between A and T

A

2

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14
Q

What is meant by antiparallel and how does this effect DNAs structure?

A

Strands run in opposite direction

This causes the strand to twist and form a double helix

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15
Q

How is DNA purified?

A

It can be purified by a precipitation reaction

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16
Q

Why does DNA replicate?

A

Before cell divisions o each new cell can have a full amount of genetic information
This is important in passing genes generation to generation

17
Q

How is DNA replicated?

A
  1. DNA helicase breaks hydrogen bonds between the strands, forming two single strands
  2. Each original strand acts as a template. Free floating DNA nucleotides join to exposed bases
  3. DNA polymerase joins them together forming hydrogen bonds
18
Q

What is a gene?

A

It is a sequence of DNA nucleotides that codes for a polypeptide.

19
Q

What is a codon?

A

Three bases making up a amino acid

20
Q

What is a single polynucleotide called?

A

RNA

21
Q

What is the function of mRNA?

A

Made in transcription.

It carried genetic code from the DNA in the nucleus to the cytoplasm where it is used to make protein during translation

22
Q

What is the function of tRNA?

A

Carried the amino acids that are used to make proteins to the ribosomes

23
Q

What is the function of rRNA?

A

The rRNA in the ribosome helps to catalyse the formation of peptide bonds between the amino acids

24
Q

What is transcription?

A

The first stage of protein synthesis. Where mRNA makes a copy of a gene

25
Q

How does transcription take place?

A
  1. RNA polymerase attaches to the DNA
  2. Complementary mRNA is formed
  3. RNA polymerase moves down the DNA strand
  4. mRNA leaves the nucleus
26
Q

What is translation?

A

This is the second stage of photosynthesis.
It takes place in the ribosomes in the cytoplasm.
Amino acids are joined together by a ribosome to make a polypeptide chain (protein)

27
Q

How does translation take place?

A
  1. mRNA attaches itself to a ribosome and tRNA molecules carry amino acids to the ribosome
  2. tRNA begin joining base pairings
  3. rRNA in the ribosome catalyses the formation of a peptide between the two amino acids