Numbers: IL, IFN, LT, CD, Complement Flashcards
(30 cards)
Major chemotactic factor for neutrophils
IL-8
LTE4
C5a
IL-6
Secreted by macrophages
Causes fever and stimulates acute phase reactions
HLA subtype associated with celiac
DQ2
DQ8
IL-10
Inhibitory/modulatory
Secreted by Th2, and regulatory T cells
Il-1
AKA osteoclast activating factor
Fever, inflammation
Causes endothelium to express adhesion molecules
Induces chemokine secretion to recruit WBCs
Complement proteins causing anaphylaxis
C3a, C4a, C5a
Decay-accelerating factor is AKA
CD55
B27 associated with
Psoriatic arthritis
Ankylosing spondylitis
IBD arthritis
Reactive arthritis (Reiter syndrome)
Receptor for EBV
CD21 on B cells
Expresses CD4, CD25
Regulatory T cells
CD16
NK cells, binds
Enhances activity of NK cells
IL-2
IL-12
IFN-a
IFN-B
HLA subtype associated with Rheumatoid Arthritis
DR4
4 walls in a rheum
Glycoproteins synthesized by virus-infected cells that prime nearby cells for defense
IFN-a
IFN-b
CD56
NK cells
Regulatory T cells identified by expression of
CD3 - all T cells
CD4 - all Th cells
CD25, FOXP3
Antibody-dependent cell-mediated cytotoxicity involves binding of what
CD16 (NK) on Fc region of a bound Ig
IL-12
Secreted by macrophages
Activates NKC
Th0–>Th1 differentiation
Mediates septic shock
Causes cachexia in malignancy
TNF-a
CD34
hematopoetic stem cells
HLA subtype associated with Hashimoto’s
DR3
DR5
Complement protein for opsonization
C3b
CD14, CD40
MHCII, B7
Macrophages
HLA subtype associated with Goodpasture syndrome
DR2
