OB Flashcards

1
Q

How long should pts wait to get pregnant after Tx for melanoma?

A

At least 3-5yrs

90% of recurrences occur within 5yrs

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2
Q

Most appropriate next step to attempt to resolve shoulder dystocia after McRoberts/suprapubic pressure

A

Delivery of the posterior arm

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3
Q

Endometrial Cancer Risk Factors Mnemonic

A

ENDOMET (Elderly, Nulliparity, Diabetes, Obesity (BMI 30+), Menstrual irregularity, Estrogen monotherapy, hyperTension)

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4
Q

HPV induces dysplasia by promoting the degradation of p53 via the expression of what?

A

E6 and E7 genes

E6 & E7 gene expression is a key element in the pathogenesis of malignant disease

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5
Q

Test used to Dx SUI?

A

Cough stress test

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6
Q

How many days after fertilization is embryo transfer assoc. w highest implantation and live birth rates?

A

5 (blastocyst stage)

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7
Q

Tx for central precocious puberty?

A

Gn-releasing hormone agonist

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8
Q

Tx of McCune-Albright?

A

Letrozole ( an aromatase inhibitor)

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9
Q

Presents w painful lesions, vesicles on erythematous base, primary infection may also cause systemic Sxs and tender lymphadenopathy

A

HSV

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10
Q

Prior to what GA is the use or cytotec for IOL acceptable for pts w prior c-section?

A

28wks

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11
Q

This aromatase inhibitor prevents the cnvsn of androgens to estrogens/ is typically used In Postmenopausal women w ER & PR + cancers

A

Anastrozole

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12
Q

This monoclonal Ab binds to the HER2/neu oncogene receptor & prevents cell proliferation

A

Trasztuzumab

(which can cause severe cardiotoxicity)

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13
Q

How many kilocalories per day are recc in 2nd trimester of pts w nml BMI?

A

340 additional kilocalories per day

No additional cals in 1st trimester, 450 in 3rd

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14
Q

Transilluminating for accessory port placement heps avoid injury to what?

A

Superficial epigastric aa.

Inferior epig aa. Tend to course beneth these but are too deep to be seen by transiluminating

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15
Q

What CA125 level should you refer a pt to Gyn Onc in the pre-menopausal period?

A

> 200

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16
Q

A pt at 8wks GA complains of rash, malaise, myalgias, the pt is tests + for CMV IgG and IgM, next step in diagnosis?

A

Avidity testing

A high-avidity IgG suggests old infection, low acidity suggests recent infection

17
Q

Most imp hormone measured to confirm menopausal status? Levels above what are considered menopausal?

A

FSH

40

18
Q

Pts typically present w a painful genital ulcer 1-2cm in size w clearly demarcated edges, may also have inguinal lymphadenopathy

A

Chancroid - rare infection caused be Haemophilus ducreyi, a gram Neg ROD
(Rare in US, May be seen in sex workers)

19
Q

Preferred initial Tx for Chancroid (2 good options)

A

Azithro or Ceftriaxone

Consider empiric Tx for syphilis

20
Q

What is polypropylene?

A

Aka Prolene- a synthetic, monofilament, nonabsorbable suture

21
Q

What is polyglactin 910 ?

A

Vicryl!

22
Q

When is cervical cancer an indication for cesarean delivery? (In those who chose to cont the preg)

A

Stage 1B1 or greater, And stage 1A1/1A2 with POS margins on cone performed during preg

23
Q

Contraindications for COCPs in women with DM?

A

Evidence of microvascular disease (retino-,nephro-, or neuro- pathy) or Duration of DM >20 yrs

24
Q

MC chemo regimen for granulosa cell tumors?

A

Bleomycin, Etoposide, and cisplatin (Platinum) ie BEP protocol

25
Q

An embryo with a crown-rump length greater than or equal to what is considered nonviable in the absence of cardiac activity

A

7 mm

26
Q

At what CA125 level should you refer a post-menopausal pt to Gyn Onc?

A

Greater than 35

International units/mL

27
Q

4 reasons to refer a premenopausal pt w a newly Dxed pelvic mass to Gyn Onc?

A
  • CA125 greater than 200
  • Ascites
  • evidence of Mets (by exam or imaging)
  • FH of breast or ovarian Ca in a 1st degree relative
28
Q

Perioperative use of garlic, ginkgo and ginseng have all been associated with?
(Ginseng can also cause what perioperatively?)

A

Increased risk of bleeding ;

Hypoglycemia

29
Q

MC side effects of AIs?

A

Menopausal Sxs, joint and muscle pain

30
Q

Competitively inhibits 5a-reductase-> inhibits cnvsn of T to DHT-> decreased DHT levels used for androgenic alopecia/ BPP/ off label for hirsutism

A

Finasteride

31
Q

What parameters on fetal umbilical artery blood gas are consistent w a peripartum or intrapartum fetal hypoxic event?

A

PH <7.15, base deficit of >/=12 or both

32
Q

At what gestational age should crown rump length no longer be used to data pregnancy but biometry should be used

A

At 14.0wks and beyond (=CRL of 84mm)

33
Q

Pts w hypogonadotropic hypogonadism will respond best to what type of ovulation induction?

A

Urinary human menopausal gonadotropins (which contain LH and FSH)

34
Q

Infant born w cataracts, patent ductus and hearing loss, what is the most likely inutero infection?

A

Rubella