obligate intracellular bacteria Flashcards

1
Q

mycoplasma

A

smallest free living prokaryotic microorganisms, facultative anaerobes
- lack cell walls (gram staining not useful)

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2
Q

mycoplasma pneumoniae transmission

A

respiratory droplets (causes lower resp tract infection)

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3
Q

diagnosis and treatment of mycoplasma pneumoniae

A

IgM-specific antibody titer is diagnostic

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4
Q

mycoplasma mycoides

A

highly contagious disease called contagious bovine pleuropneumonia (transmission by aerosols with a high mortality rate)

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5
Q

sign of mycoplasma mycoides postpartum

A

pneumonic lungs will show marbling

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6
Q

cell membrane of mycoplasma species

A

sterol- containing lipid bilayer

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7
Q

where do chlamydiaceae grow?

A

cytoplasmic vacuoles in a limited number of host cell types

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8
Q

are chlamydiaceae gram - or +

A

negative

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9
Q

chlamydiae possess ______ and synthesize their own _______

A

ribosomes, protein

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10
Q

reproductive cycle of chlamydiaceae

A

1) the elementary body is taken up by phagocytosis into susceptible host cells
2) the elementary particle reorganizes into a larger, noninfectious reticulate body
3) the reticulate body divides repeatedly by binary fission, forming inclusion bodies
4) after 48 hours, multiplication ceases and reticulate bodies condense, becoming new, infectious elementary bodies
5) elementary bodies are then released from the cell by cytolysis, ending in host cell death

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11
Q

chlamydia trachomatis

A

infections of the conjuctiva or genital tract which vary depending on the biovar involved

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12
Q

trachoma

A

progressive conjunctivitis with inflammation and scarring leading to blindness

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13
Q

genital biovars

A

most common form of sexually transmitted urethritis, cervicitis, and salpingitis

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14
Q

lymphogranuloma venereum biovars cause

A

localized, ulcerative genital lesions with spread to regional lymph nodes

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15
Q

trachoma

A

spread by direct contact with the eye, nose, throat secretions from affected individuals, or contact with fomites

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16
Q

neonatal conjunctivitis

A

swelling of eyelids, hyperemia and purulent discharge beginning 2-30 days after birth

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17
Q

infant pneumonia

A

rhinitis 2-3 wks after birth and a distinctive staccato cough, no feverc

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18
Q

community acquired respiratory infection is caused by

A

chlamydia pneumoniae

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19
Q

community acquired respiratory infection causes

A

pharyngitis, laryngitis, bronchitis, sinusitis, or interstitial pneumonia

20
Q

psittacosis is caused by

A

chlamydia psittaci

21
Q

how is psittacosis transmitted

A

through inhalation of contaminated dust containing bird feces

22
Q

what does psittacosis affect

A

lower resp tract, causing fever, dry cough, flu like symptoms & patchy pulmonary infiltration

23
Q

rickettsiaceae

A

obligate intracellular gram- negative bacilli
- cell walls contain peptidoglycan
only grow inside living host cells

24
Q

rickettsiaceae causes

A

systemic diseases that are mainly arthropod borne in humans and animals

25
Q

rocky mountain spotted fever organism

A

rickettsiaceae rickettsii

26
Q

rocky mountain spotted fever vector

A

tick

27
Q

rocky mountain spotted fever clinical features

A

inward- spreading macular rash (abrupt onset)

28
Q

epidemic typhus orgnaism

A

rickettsiaceae prowazekii

29
Q

epidemic typhus vector

A

lice (defecate while feeding and they also die from the infection)

30
Q

epidemic typhus clinical features

A

arthralgia; outward spreading macular rash
- abrupt onset

31
Q

endemic typhus organism

A

rickettsiaceae typhi

32
Q

endemic typhus vector

A

flea (rat flea xenopsylla cheopsis)

33
Q

endemic typhus clinical features

A

gradual onset of fever, headache, myalgia, and cough; maculopapular rash on trunk

34
Q

rickettsial pox organism

A

rickettsiaceae akari

35
Q

rickettsial pox vector

A

mites

36
Q

rickettsial pox clinical features

A

generalized papulovesicular rash accompanied by sloughing
- abrupt onset

37
Q

human monocytic ehrlichiosis (HME) caused by

A

ehrlichia chaffeensis

38
Q

human monocytic ehrlichiosis (HME) vector

A

lone star tick

39
Q

human monocytic ehrlichiosis (HME) clinical signs

A

acute fever, myalgia, leukocytopenia and thrombocytopenia

40
Q

human granulocytic anaplasmosis (HGA) caused by

A

anaplasma phagocytophilum

41
Q

human granulocytic anaplasmosis (HGA) vector

A

deer and dog tick

42
Q

human granulocytic anaplasmosis (HGA) clinical signs

A

more severe fever, myalgia, leukocytopenia and thrombocytopenia

43
Q

Q fever organism

A

coxiella burnetti

44
Q

coxiella burnetti gram stain

A

poor. better stained with giemsa or gimenez stains. gram negative

45
Q

q fever

A

zoonotic from cattle, sheep, and goat - airborne transmission to farm workers, vets