obligate intracellular bacteria Flashcards

(45 cards)

1
Q

mycoplasma

A

smallest free living prokaryotic microorganisms, facultative anaerobes
- lack cell walls (gram staining not useful)

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2
Q

mycoplasma pneumoniae transmission

A

respiratory droplets (causes lower resp tract infection)

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3
Q

diagnosis and treatment of mycoplasma pneumoniae

A

IgM-specific antibody titer is diagnostic

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4
Q

mycoplasma mycoides

A

highly contagious disease called contagious bovine pleuropneumonia (transmission by aerosols with a high mortality rate)

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5
Q

sign of mycoplasma mycoides postpartum

A

pneumonic lungs will show marbling

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6
Q

cell membrane of mycoplasma species

A

sterol- containing lipid bilayer

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7
Q

where do chlamydiaceae grow?

A

cytoplasmic vacuoles in a limited number of host cell types

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8
Q

are chlamydiaceae gram - or +

A

negative

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9
Q

chlamydiae possess ______ and synthesize their own _______

A

ribosomes, protein

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10
Q

reproductive cycle of chlamydiaceae

A

1) the elementary body is taken up by phagocytosis into susceptible host cells
2) the elementary particle reorganizes into a larger, noninfectious reticulate body
3) the reticulate body divides repeatedly by binary fission, forming inclusion bodies
4) after 48 hours, multiplication ceases and reticulate bodies condense, becoming new, infectious elementary bodies
5) elementary bodies are then released from the cell by cytolysis, ending in host cell death

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11
Q

chlamydia trachomatis

A

infections of the conjuctiva or genital tract which vary depending on the biovar involved

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12
Q

trachoma

A

progressive conjunctivitis with inflammation and scarring leading to blindness

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13
Q

genital biovars

A

most common form of sexually transmitted urethritis, cervicitis, and salpingitis

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14
Q

lymphogranuloma venereum biovars cause

A

localized, ulcerative genital lesions with spread to regional lymph nodes

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15
Q

trachoma

A

spread by direct contact with the eye, nose, throat secretions from affected individuals, or contact with fomites

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16
Q

neonatal conjunctivitis

A

swelling of eyelids, hyperemia and purulent discharge beginning 2-30 days after birth

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17
Q

infant pneumonia

A

rhinitis 2-3 wks after birth and a distinctive staccato cough, no feverc

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18
Q

community acquired respiratory infection is caused by

A

chlamydia pneumoniae

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19
Q

community acquired respiratory infection causes

A

pharyngitis, laryngitis, bronchitis, sinusitis, or interstitial pneumonia

20
Q

psittacosis is caused by

A

chlamydia psittaci

21
Q

how is psittacosis transmitted

A

through inhalation of contaminated dust containing bird feces

22
Q

what does psittacosis affect

A

lower resp tract, causing fever, dry cough, flu like symptoms & patchy pulmonary infiltration

23
Q

rickettsiaceae

A

obligate intracellular gram- negative bacilli
- cell walls contain peptidoglycan
only grow inside living host cells

24
Q

rickettsiaceae causes

A

systemic diseases that are mainly arthropod borne in humans and animals

25
rocky mountain spotted fever organism
rickettsiaceae rickettsii
26
rocky mountain spotted fever vector
tick
27
rocky mountain spotted fever clinical features
inward- spreading macular rash (abrupt onset)
28
epidemic typhus orgnaism
rickettsiaceae prowazekii
29
epidemic typhus vector
lice (defecate while feeding and they also die from the infection)
30
epidemic typhus clinical features
arthralgia; outward spreading macular rash - abrupt onset
31
endemic typhus organism
rickettsiaceae typhi
32
endemic typhus vector
flea (rat flea xenopsylla cheopsis)
33
endemic typhus clinical features
gradual onset of fever, headache, myalgia, and cough; maculopapular rash on trunk
34
rickettsial pox organism
rickettsiaceae akari
35
rickettsial pox vector
mites
36
rickettsial pox clinical features
generalized papulovesicular rash accompanied by sloughing - abrupt onset
37
human monocytic ehrlichiosis (HME) caused by
ehrlichia chaffeensis
38
human monocytic ehrlichiosis (HME) vector
lone star tick
39
human monocytic ehrlichiosis (HME) clinical signs
acute fever, myalgia, leukocytopenia and thrombocytopenia
40
human granulocytic anaplasmosis (HGA) caused by
anaplasma phagocytophilum
41
human granulocytic anaplasmosis (HGA) vector
deer and dog tick
42
human granulocytic anaplasmosis (HGA) clinical signs
more severe fever, myalgia, leukocytopenia and thrombocytopenia
43
Q fever organism
coxiella burnetti
44
coxiella burnetti gram stain
poor. better stained with giemsa or gimenez stains. gram negative
45
q fever
zoonotic from cattle, sheep, and goat - airborne transmission to farm workers, vets