ODANSETRON (ZOFRAN)

Question 1

CLASS

Answer 1

ANTIEMETIC

Question 2

DESCRIPTION

Answer 2

BLOCKS 5-HT3 RECEPTORS TO STOP VOMITTING & NAUSEA

Question 3

ONSET AND DURATION

Answer 3

ONSET- WITHIN 30 MINUTES
DURATION- 3-6 HOURS

Question 4

INDICATIONS

Answer 4

-NAUSEA
-VOMITING

Question 5

CONTRADICTIONS

Answer 5

-HYPERSENSITIVITY
-ADMINISTRATION WITH APOMORPHINE
-LIVER DISEASE
-GI OBSTRUCTION
-PROLONGED QT SYNDROME

Question 6

ADVERSE REACTIONS

Answer 6

GENERALLY WELL TOLERATED
ECG IRREGULARITIES
HICCUPS, HEADACHE, DIZZINESS, DROWSINESS, SHIVERING, HYPOXIA
PRURITUS, FLUSHING, CHILLS,

Question 7

DRUG INTERACTIONS

Answer 7

NONE

Question 8

DOSAGES

Answer 8

IV: 4 MG IV/IM MAY BE GIVEN UNDILUTED INJECTED OVER 30 SECONDS
IM: 4MG SINGLE INJECTION IN WELL DEVELOPED MUSCLES.

Question 9

SPECIAL CONSIDERATIONS

Answer 9

PREGNANCY SAFTEY- CATEGORY B
-MAY MASK THE SYMPTOM OF OTHER GI PROBLEMS
- TABLETS SHOULD GENTLY BE REMOVED FROM FOIL AND NOT PUSHED THROUGH FROM PACKAGE
- ALLOW ODT TO DISSOLVE ON TONGUE WITH SALIVA
- MAY PROLONG QT INTERVAL

Question 10

HOW ODANSETRON (ZOFRAN) IS SUPPLIED