Olanzapine

Question 1

What is the mechanism of action for Olanzapine?

Answer 1

●Atypical antipsychotic.
●Has actions at multiple receptors within the brain causing…
-A reduction in agitation.
-Sedation.
-Anxiolysis.
-Mood stabilisation.

Question 2

What are the indications for Olanzapine?

Answer 2

●Aged 12 and over with acute behavioural disturbance causing mild-moderate risk to safety when they will take an oral medication.

Question 3

What are the contraindications of Olanzapine?

Answer 3

●Known severe allergy.
●Poisoning with an antipsychotic such as Quetiapine, Resperidone, or Olanzapine.

Question 4

What are the cautions for Olanzapine? (3)

Answer 4

●Pregnancy.
●Intoxication, will increase/prolong effects.
●75 or greater particularly if frail, increases/prolongs effects.

Question 5

What are the adverse effects for Olanzapine?

Answer 5

Sedation.

Question 6

What is the dose for Olanzapine?

Answer 6

10mg per oral.
Reduce to 5mg if caution is present.
Can be repeated once only after 20 minutes.