Oncogene or Tumor Suppressor? w/tumor Flashcards

0
Q

PTEN

A

Tumor suppressor

Glioblastoma, melanoma, prostate, breast, endometrial, thyroid, lung, colorectal, AML, CLL

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1
Q

APC

A

Tumor suppressor

Colorectal, gastric

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2
Q

H-RAS

A

Oncogene

Bladder

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3
Q

MYC

A

Oncogene

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4
Q

Rb

A

Tumor suppressor

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5
Q

p116(INK)

A

Tumor suppressor

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6
Q

EGFR

A

Oncogene

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7
Q

KIT

A

Oncogene

Gastrointestinal stromal tumors, melanoma, AML

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8
Q

BRCA1

A

Tumor suppressor

Breast, ovarian

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9
Q

BCR-ABL

A

Oncogene

CML, ALL, AML

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10
Q

p14(ARF)

A

Tumor suppressor

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11
Q

p110a (alpha)

A

Oncogene

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12
Q

JAK2

A

Oncogene

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13
Q

LKB1

A

Tumor suppressor

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14
Q

N-RAS

A

Oncogene

Melanoma, AML

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15
Q

VHL

A

Tumor suppressor

Kidney, adrenal, hemangoiblastoma

16
Q

FLT-3

A

Oncogene

17
Q

FBXW7

A

Tumor suppressor

18
Q

MET

A

Oncogene

19
Q

IDH2

A

Oncogene

20
Q

IDH1

A

Oncogene

21
Q

NF1

A

Tumor suppressor

22
Q

p53

A

Tumor suppressor

23
Q

B-RAF

A

Oncogene

24
Q

NF2

A

Tumor suppressor

25
Q

BRCA2

A

Tumor suppressor

Breast, ovarian

26
Q

HER2 (ERB B2)

A

Oncogene

27
Q

K-RAS

A

Oncogene