Oncology

Question 1

Ca19-9

Answer 1

Pancreatic

Question 2

CEA

Answer 2

Colorectal

Question 3

HNPCC caner

Answer 3

Colorectal and endometrial

Question 4

AFP

Answer 4

Liver, testicular

Question 5

Chromogranin A

Answer 5

Carcinoid (bronchial carcinoid tumour)

Question 6

Carcinoid tumour management

Answer 6

Ocreotide

Question 7

SIADH is associated with which malignancy

Answer 7

Small cell

Question 8

Small cell cancer chemo agents

Answer 8

Cisplatin and etoposide

Question 9

Non small cell cancer chemo agents

Answer 9

Carboplatin and paclitaxel

Question 10

Cancer that kills most women in the UK

Answer 10

Lung

Question 11

Most common cancer in the UK for women

Answer 11

Breast

Question 12

Oesophageal adenocarcinoma histology

Answer 12

Tubo-papillary growth

Question 13

Ca153

Answer 13

Breast

Question 14

Ca125

Answer 14

Ovarian

Question 15

Vinyl chloride

Answer 15

Haemangiosarcoma of the liver

Question 16

Nickel

Answer 16

Cancer of the oral cavity

Question 17

Arsenic

Answer 17

Skin cancer

Question 18

EBV

Answer 18

Lymphoma - Hodgkins and Burkitts

Question 19

Human herpes virus 8

Answer 19

Kaposi’s sarcoma

Question 20

Human T lymphocyte virus

Answer 20

Leukaemia

Question 21

Hepatitis B

Answer 21

Liver

Question 22

Lymphoma investigation

Answer 22

Excisional biopsy (not FNB as can miss cancer cells)

Question 23

Paraneoplastic cerebellar degeneration antibody

Answer 23

anti-Yo

Question 24

Why is HCC more common in China

Answer 24

Large number of hepatitis B patients

Question 25

Burkitts lymphoma

Answer 25

c-MYC starry sky

Question 26

What is CEA used for

Answer 26

Post op surveillance colon cancer

Question 27

Blood film finding for a patient with prostate cancer

Answer 27

Leukoerythroblastic picture

Question 28

Which side varicocele in renal cancer

Answer 28

LHS

Question 29

Imatininb moa

Answer 29

Tyrosine kinase inhibitor

Question 30

How do SCC spread

Answer 30

Lymphatics

Question 31

Which cancers respond well to imatinib

Answer 31

GIST and CML

Question 32

Phase I trial

Answer 32

Looks at human toxicity and pharmacokinetics

Question 33

Phase II trial

Answer 33

Establish anti-tumour effet of drug

Question 34

Phase III trial

Answer 34

Compares new drug to best conventional therapy

Question 35

Phase IV trials

Answer 35

Look at long term effects of drug

Question 36

What does R mean in cancer staging

Answer 36

Residual volume of cancer left

Question 37

Non invasive bladder cancer treatment

Answer 37

TURBT and mitomycin C (if muscle invasive can give BCG)q

Question 38

Which part of the cell cycle are cells least likely to respond to chemo

Answer 38

G0

Question 39

Chronic gastritis, type of cancer related

Answer 39

MALT lymphoma