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Flashcards in Oncology Deck (8):
1

Wilm's Tumor/Nephroblastoma

Commonly presents as asymptomatic mass with mean age of dx of 3.5. Abdo pain (40%), hematuria (20%), hypertension, hemihypertrophy and aniridia.
Metastasize by blood/lymph: bone, lung, brain, liver.
Good prognosis, 80-90% survival with chemo, radiation and surgery.
Aniridia and wilm's are both associated with Chromosome 11.

2

Acute splenic sequestration
bite cells and Heinz bodies. big sequestration of cells into the spleen causing hypovolemia and circulatory collapse.

bite cells and Heinz bodies. big sequestration of cells into the spleen causing hypovolemia and circulatory collapse.

3

Beckwidth Wiedeman Syndrome

Overgrowth disorder. Macrosomia, visceromegaly, macroglossia, hyperinsulinemic hypoglycemia, midline defects. Ear tags/pits. Associated with wilm's Tumor.

4

WAGR Syndrome

Wilm's Tumor, Aniridia, GU abnormalities, mental retardation.

5

Fever, abdominal mass, bone pain, limp, irritability and diarrhea....

neuroblastoma probably.

6

Prognostic factors for ALL

Bad: thymic variants mostly - age 10, CNS leukemia, platelets <100 000, mediastinal mass.

7

Acute splenic sequestration

bite cells and Heinz bodies. big sequestration of cells into the spleen causing hypovolemia and circulatory collapse.

7

Drugs causing mucositis

Methotrexate usually. Also doxorubicin.