one health and pandemics Flashcards

(40 cards)

1
Q

what is an endemic

A

Endemic meansa disease that is always present in a population within a geographic area, typically year-round.

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2
Q
  • epidemic vs pandemic
A

While an epidemic is large, it is also generally contained or expected in its spread, while a pandemic is international and out of control

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3
Q

What is “One Health’’

A

an approach that recognises that the health of people is closely connected to the health of animals & our shared environment: it looks at how interdependent human and animal health is, and how it links to outside.

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4
Q

examples of one health

A

how we have diet and biodiversity loss and air pollution and disease vectors and population movement all linked

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5
Q

what is zoonotic spillover

A

The transmission of pathogens from wild animals to humans is called “zoonotic spillover”.

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6
Q

what % of human infectious diseases are derived from pathogens that originally circulated in non-human animal species

A

60-75%

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7
Q

example of one zoonotic spillover disease

A

e.g. bird flu can mix with something easily spread, like another influenza virus, it can have a zoonotic spillover into humans.

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8
Q

how do germs spread between animals and people? (5)

A
  • Direct contact:
  • indirect contact:
  • Vector-borne:
  • Foodborne:
  • Waterborne:
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9
Q

direct contact

A

Coming into contact with the saliva, blood, urine, mucous, feces, or other body fluids of an infected animal. Examples include petting or touching animals, and bites or scratches

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10
Q

indirect contact

A

Coming into contact with areas where animals live and roam, or objects or A surfaces that have ben contaminated w surfaces that have been contaminated with germs. Examples include aquarium tank water, hti germs. e.g. include aquarium tank water, pet habitats, chicken coops, barns, plants, and soil, as well as pet food and water dishes.

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11
Q

vector borne method

A

Being bitten by a tick, or an insect like a mosquito or a flea.

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12
Q

food borne method

A

Each year, 1/6 Americans get sick from eating contaminated food. Eating or drinking something unsafe, such as unpasteurized (raw) milk, undercooked meat or eggs, or raw fruits and vegetables that are contaminated with feces from an infected animal. Contaminated food can cause illness in people and animals, including pets.

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13
Q

waterborne

A

Drinking or coming in contact with water that has been contaminated with feces from an infected animal.

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14
Q

common one Health issues include

A

emerging, re-emerging, and endemic zoonotic diseases, neglected tropical diseases, vector-borne diseases, antimicrobial resistance, food safety, and food security, environmental contamination, climate change and other health threats shared by people, animals, and the environment.

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15
Q

Antibimicrobial-resistant germs are an issue why? for one health

A

they quickly spread through communities, the food supply, healthcare facilities, and the environment (soil, water), making it harder to treat certain infections in animals and people.

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16
Q

Vector-borne diseases are a bigger issue now why?

A

warmer temperatures and expanded mosquito and tick habitats.

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17
Q

Diseases in food animals can threaten

A

supplies, livelihoods, and economies.

18
Q

what effect do intensive farming techniques have on pandemics

A

increase the likelihood of pathogens becoming a major public health risk through

19
Q

how does intensive farming inc the risk of pandemic (4)

A
  1. Overuse of antibiotics in livestock.
  2. High animal numbers in small spaces/ hygiene standards.
  3. Low genetic diversity
  4. Deforestation /Encroachment into wildlife habitats
20
Q

Shifting climatic conditions drive alterations in what?

A

both host & vector spatial distributions, population densities, pathogen load in individuals, & the prevalence of pathogens in potential animal reservoirs.

21
Q

examples of global health emergency risk factors include:

A
  • Climate Change
  • Globalization
  • Intensive factory farming & loss of biodiversity
  • Deforestation/ increasing contact with wild animals
  • Growth of megacities (people living in crowded conditions)
  • Weak health systems and shortage of healthworkers - Socio-economic factors.
  • Vaccine hoarding
22
Q

Climate Change affects Human Health in direct ways how

A

these include extreme weather events that cause
1. storms
2. floods
3. droughts

23
Q

Climate Change affects Human Health in indirect ways how

A
  • indirect risks are mediated through
    1. water quality
    2. air pollution
    3. changes in biosphere (distribution of disease vectors)
    4. food availability / security linked to land use
24
Q

definition of a public health emergency of international concern

A

“an extraordinary event that may constitute a public health risk to other countries through international spread of disease and may require an international coordinated response.” The purpose of the declaration is to focus international attention on a cute public health risks that “require coordinated mobilisation of extraordinary resources by the international community” for prevention and response.

25
how many events were declared PHEIC between 2007 and 2025
7
26
examples of PHIEC events
- 2009 1) **H1N1** influenza pandemic 2009 - ebola West African outbreak 2013-2015, - outbreak in Democratic Republic of Congo 2018-2020 - **Poliomyelitis** (2014 to present) – longest PHEIC - the first PHEIC for an arboviral disease zika 2016 - covid 19 (Jan 2020 to May 2023) - m pox July 2022- May 2023) and (Aug 2024 – current)
27
lessons from covid 19
1. invest in pandemic preparedness 2. vaccine equity and manufacturing in LMIC settings 3. need for WHO pandemic treaty 4. risk communication/public engagement
28
what were the legal barriers to vaccine equity
Legal Barriers: Patents (TRIPS Doha Declaration) / Technology transfer, indemnity
29
what occurred with vaccines during swine flu
vaccine hoarding
30
why is vaccine Production (mRNA vs traditional vaccines) an issue
mRNA vaccines require different technology and cold chain logistics, complicating production for LMICs.
31
Lack of manufacturing capacity where had what effect?
LMICs/LICs forced dependence on HICs (*with notable exceptions (for example, China, Cuba, and India))
32
what is covax
**COVAX** (COVID-19 Vaccines Global Access) is a global initiative co-led by: - **Gavi** (the Vaccine Alliance) - **CEPI** (Coalition for Epidemic Preparedness Innovations) - **WHO** (World Health Organization)
33
purpose of covax
To ensure equitable access to COVID-19 vaccines for all countries, regardless of income level, especially low- and middle-income countries (LMICs).
34
COVAX limitations
- Supply shortages and delays. - HICs bought up doses directly from manufacturers, bypassing COVAX. - Funding gaps and limited bargaining power. - Struggled to meet its goals in the early pandemic stages
35
why is Vaccine Deployment such a big issue
- Training HCWs and overall lack of health workers Because without enough trained staff, it's difficult to store, handle, and administer vaccines safely and efficiently. - Challenges with ultra-cold chains LMICs lack the infrastructure to maintain ultra-low temperatures needed for mRNA vaccines, limiting access and distribution. - IT Challenges Weak digital systems make it hard to track inventory, appointments, and patient records, leading to inefficiencies. - Vaccine wastage - Substandard and Falsified COVID19 vaccines undermine public trust, waste resources, and put lives at risk, especially in countries with weak regulatory systems
36
how could we help with vaccine deployment
- Could use pre-filled devices in LMIC settings to increase efficiency They reduce preparation time, human error, and wastage, making mass vaccination more efficient.
37
what causes vaccine inequity
Lack of transparency in vaccine prices across countries & companies contributed to vaccine inequity The lack of transparency around vaccine prices and terms of contracts, including indemnity, has been a barrier to countries being able to negotiate and buy vaccines even when resources were available—a problem that was particularly acute for Latin America.
38
e.g. how much did diff countries pay per dose of the oxford astra zeneca vaccine?
In 2021: EU paid = $3.50 (£2.70; €3.20), South Africa was being charged $5.25, Uganda was being charged $7. - Many LMICs had to take out loans to procure vaccines for their populations while high covid-19 vaccine prices have led to huge profits for industry.
39
Describe what the impacts of climate change may be on the health of the public e.g. through food availability / security linked to land use
e.g. droughts reduce crops → undernutrition, especially in LMICs.
40
Describe what the impacts of climate change may be on the health of the public e.g. through air pollution: e.g. wildfires and fossil fuels
↑ particulate matter → be specific: inc ↑ asthma, lung cancer, cardiovascular disease.