Opthalmic Miotics Flashcards

1
Q

Miotics do what

A

CONSTRICT pupils; used to lower intraocular pressure (ICP)

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2
Q

2 types of miotics

A

direct acting cholinergic and indirect acting anticholinesterase drugs

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3
Q

what do miotic direct acting cholinergics do

A

mediate transmission of nerve impulses at all parasympathetic nerve sites (similar to acetylcholine)

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4
Q

what is the therapeautic use of miotic direct acting cholinergic

A

opthalmic procedures

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5
Q

examples of miotic direct acting cholinergic

A

pilocarpine (Isopto carpine, pilopine HS, Ocusert disk pilo-20 and 40; binds to ocular tissue)

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6
Q

what do miotic indirect acting cholinesterase do

A

inactivate cholinesterase resulting in pupil constriction, thus reducing intraocular pressure

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7
Q

what is the therapeautic use of miotic indirect acting cholinesterase

A

reduce intraocular pressure

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8
Q

examples of miotic indirect acting cholinesterase

A

physostigmine salicylate (Isopto Eserine)

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9
Q

what are common s/e of miotics, if absorbed into the system

A

HA, eye and brow pain, decreased vision; systemic absorption: n/v/d, polyurea, asthma attack, drooling, diaphoresis

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10
Q

how to prevent s/e of miotics

A

apply gentle pressure on lacrimal duct for 1-2 min; lacrimal duct carries fluid to nose.

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11
Q

give what if overdose in cholinesterase inhibitor?

A

mydriatic atropine sulfate

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12
Q

Miotics Toxicity s/e are

A

vertigo, bradycardia, tremors, hypotension, syncope, dysrhythmia, seizure; give Atropine Sulfate.

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13
Q

Miotics are contrainidicated for pts with

A

retinal detachment, adhesion between iris and lens, ocular infection

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