Oral Cavity Path II Flashcards Preview

GI II Exam 1 > Oral Cavity Path II > Flashcards

Flashcards in Oral Cavity Path II Deck (58):
1

oral hairy leukoplakia

immunosuppression and EBV

lateral border of tongue

2

lateral tongue, white, doesn't scrape

oral hairy leukoplakia

**do an HIV test

balloon cells

3

balloon cells

oral hairy leukoplakia

4

black hairy tongue

poor hygiene
-don't scrape off and debride surface of tongue

tobacco, coffee, tea

5

rash with ampicilin

mononucleosis

6

monospot test

neurophile antibodies - for EBV
-mono test

7

other mono test

mix serum from patient with sheep/horse RBCs
-EBV - creates heterophile antibodies
-positive - agglutination of RBCs - clumping

8

mononucleosis

hyperemic mucosa - posterior pharynx

9

irritation fibroma

bite line - tongue or mucosa
-repetitive trauma

reactive fibroblast tissue

tx - surgical excision

10

pyogenic granuloma

gingiva, tongue
-pregnancy tumor

reactive granulation tissue
-benign inflammatory vascular lesion
-may bleed

common in young people

tx - surgical excision

11

pregnancy tumor

pyogenic granuloma

granulation tissue

12

cancer of oral cavity

95% SCC
5% adenocarcinoma of salivary glands

tobacco and alcohol

india - chew betel quid and paan

oral pharynx - type 16 HPV

13

posterior pharynx cancer

HPV - 16 and 18

14

anterior mouth cancer

tobacco

15

cells pass BM

metastasis

need biopsy to determine lesion is malignant

16

leukoplakia

white patch/plaque
-cannot be scraped off

due to increased keratin

17

hyperkeratosis

not premalignant change

bx needed

18

erythroplakia

red patch
-less common than leukoplakia but more ominous
-90% dysplasia or CIS

highly vascular eroded mucosa

19

keratin peral

squamous cell carcinoma

20

oral SCC

80% are stage II/III with high rate of recurrence

21

stage 3 and 4 SCC

always radiation

22

CIS SCC of oral cavity

treated like stage 1 - primary surgery/ radiation

23

five hear survival stage 1/2 SCC

70-90%
-need careful follow up

increased risk of second head and neck cancer as well as lung ca

24

wide local excision

oral cavity cancers

25

transoral laser resection

oropharynx, hypopharynx, larynx

26

strawberry tongue

scarlet fever

27

koplik spots

measles

28

acute pharyngitis and tonsillitis - gray white exudative membrane

infectious mono

29

wartons duct

submandibular gland
-gleeking

30

salivary glands

parotid - serous
submandibular - mixed
sublingual - mixed

31

minor salivary glands

lubrication
-buccal, gingival, palatal mucosa

32

acute b/l tender swelling of parotid and salivary glands lasting 2 days

mumps
-virus

33

mumps complication

testicular inflammation - orchitis

sterility may occur

34

parotitis

swelling of parotid gland
-mumps

may last up to 10 days

35

mumps vaccine

MMR

third dose - in outbreak setting

contraindication - pregnant, immunosuppressed, malignancy

36

sjogrens syndrome

third most common autoimmune
-female age 40yo

autoAbs agasinst Ags in salivary glands and lacrimal glands

37

keratoconjunctivitis and xerostomia

sjogrens

dry eyes and dry mouth

38

sicca syndrome

dry eyes and mouth
-sjogrens

39

severe sjogrens

risk of NHL

40

diagnosis of xerostomia

bx of salivary gland
-see lymphocytes attacking glands

41

sjogrens association

rheumatoid arthritis
SLE, polymyositis, scleroderma, vasculitis, thyroiditis

42

blurry vision, itchy, dysphagia, dry mouth, inabilty to taste

sjogrens

43

SS-A titers

extraglandular sjogrens disease - synovitis, pulmonary fibrosis, peripheral neuropathy

more likely to have early disease onset and longer duration as well

44

mikulicz syndrome

lacrimal and salivary gland enlargement from any cause

45

sjogrens dx

-biopsy
-CD4 T cells ans B cells
-rheumatoid factor - IgG
-ANAs on immunofluorescence
-SS-A and SS-B

46

mucocele

msot common lesion of salivary gland - mucous retention cyst

block of salivary gland tract

often lower lip**

tx - excision - if incomplete - recurrence occurs

47

sialolith

blockage of salivary duct - food particle = nidus

enlargement with aggregation of dehydrated mucous

often submandibular gland

48

bacterial sialadenitis

unilateral duct obstruction causes stasis

allows infection - staph aureus or strep viridans

acute inflammation - to chronic inflammation

49

benign tumors of salivary gland

pleomorphic adenima - mixed

warthin tumor

50

malignant tumor of salivary gland

mucoepidermoid carcinoma

adenoid cystic carcinoma

51

pleomorphic adenoma

mixed tumor- benign
-of salivary gland

50% of all tumors of salivary gland

epithelial and mesenchymal cells
-arise from basal myoepithelial cells

52

epihelial and myxoid tumor

pleomorphic adenoma of salivary gland

can be left in place

15 years - 10% develop to malignant

53

painless slow growing mobile discrete mass in submandibular/buccal area

pleomorphic adenoma

54

warthin tumor

papillary cystadenoma lymphomatosum

10% salivary tumors, benign
-males, 50-60yo, smokers**

parotid gland
-

55

warthin tumor bx

double layer of eosinophilic epithelial cells over lymphoid stroma*

56

malignant tumors of head and neck

adenocarcinoma
mucoepidermoid carcinoma
adenoid cystic carcinoma

57

mucoepidermoid carcinoma

parotid
-malignant
-slow growing

grade important for px
-high grade - invasive
-low-hrade - rare mets

mucicarmine stain - for mucin

and pink sqamous epidermoid cells

58

adenoid cystic carcinoma

malignant of salivary gland

infiltrate along nerve**
-perineural invasion

recurrent common

swiss cheese appearance - holes