Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Histo > oral mucosa > Flashcards

oral mucosa Flashcards

(72 cards)

Start Studying
1
Q

a mucous membrane is an organ composed of what two tissues?

A

epithelium

connective tissue: lamina propria and sometimes submucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

____ tissue is also embedded in oral mucosa, lingual, and palatine tonsils

A

lymphoid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

the oral mucosa, especially the _____, but also the ____, contain cells of the immune system that are able to mount a protective response against infection

A

lamina propria; epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

____ synthesize and secrete several immune molecules and also anti-microbial peptides, called ____

A

epithelial cells; beta-defensins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

beta defensins are ____ rich and ____

A

cysteine; cationic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

beta defensins bind to negative charges on ____ and _____

A

bacterial membranes; permeabilize

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

oral mucosa is highly innervated, which augments ____ and _____ functions

A

protective; ingestive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

all oral epithelium is classified as _____ epithelium; it is a ____ population of cells

A

stratified squamous; self-renewing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

____ (aka epithelial cells) are the most numerous in the oral epithelium

A

keratinocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

non keratinocytes in the oral epithelium

A

merkel cells - sensory- basal layers
melanocytes- pigment cells- basal layers
langerhans (dendritic) cells- immune- supra-basal layers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

____ and ____ have a distinct clear appearance in sections stained with classic H&E techniques; can be distinguished from each other by location

A

langerhans cells; melanocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

melanocytes make melanin using the enzyme _____

A

tyrosinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

alveolar mucosa is ____ while gingiva is ____

A

non-keratinized; keratinized

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

more superficial layers of keratinized and non-keratinized epithelium are distinct; keratinized epithelium has ____ layer and non-keratinized epithelium has ____ layer

A

granular; intermediate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

all epithelial cells are keratinocytes that contain ____

A

cytokeratins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

cytokeratins are a large (about 30) ____ family of proteins that assemble into _____ to provide cytoskeletal support

A

multigene; intermediate filaments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

2 major groups of cytokeratins

A

type I (acidic) and type II (basic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

cytokeratins are the intracellular component of ____ and ____

A

desmosomes; hemidesmosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

cytokeratins contribute to ____ in both keratinized and non-keratinized oral mucosa ; and in both types, amount of cytokeratin ____ in superficial layers

A

mechanical toughness; increases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

keratinized specific cytokeratins promote _____ and promote binding to another molecule, ____ (main component of keratohyalin granules)

A

aggregration (tonofibrils); fillagrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

specific nonkeratinized cytokeratin types ____ promote aggregration

A

DO NOT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

keratinized epithelium is ____ but less _____ than non-keratinized epithelium

A

tougher; flexible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

membrane coating granules are membrane bound organelles, filled with _____; first appear in ____ cell layer

A

glycolipids; upper prickle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

membrane coating granules occur in both keratinized and non-keratinized epithelia and serve as an _____ barrier to _____ substances

A

intercellular ; aqueous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
15 nm cross-linked protein sheath comprised of loricrin and other proteins
cornified envelope (of keratinized epithelium)
26
lamina propria- most volume occupied by ____
ECM
27
cells also present in the lamina propria
fibroblasts (most numerous) | macrophages, mast cells, other inflammatory cells
28
components of the ECM
PGs and GAGs glycoproteins (fibronectin) collagen (type I and III) ELASTIN
29
the relative amount of type I : type III collagen is ____ for _____ regions of the oral cavity
greater; less flexible
30
elastin is more prominent in ____ than in ___ or ____
oral mucosa; pulp; PDL
31
"stippling" of gingiva reflects underlying ____ and ____
epithelial rete pegs; connective tissue papillae
32
present under some regions of oral mucosa; contains larger BVs and nerves supplying superficial LP
submucosa
33
the submucosa contains ____ and separates the LP from ____
glands; bone and muscle
34
the lamina propria of lining mucosa has fewer ____ and more ____
collagen fibers; elastic fibers
35
the dense lamina propria of masticatory mucosa has more ____ and fewer ____
collagen fibers; elastic fibers
36
part of free gingiva which faces tooth, generally non-keratinized
sulcular epithelium
37
all components are present in the external basal lamina of the junctional epithelium, but ____ components are absent in the internal basal lamina
collagen
38
collagen components of the ____ provide direct connection to collagen of the _____
basal lamina; lamina propria
39
consistent with its origin from ____, junctional epithelium expresses a protein initially associated with _____
reduced enamel epithelium; ameloblasts (odontogenic ameloblast-associated protein or ODAM)
40
the ____ component of the oral mucosa and the ____ maintain a barrier that retards the movement of microorganisms to the underlying tissues
epithelial; basal lamina
41
types of fibers in the pulp and dentin and their functions
Adelta, C fibers, and Abeta fibers: (mostly) pain
42
types of fibers in the PDL and their functions:
Adelta and C fibers: (mostly) pain | Abeta fibers: proprioceptive
43
types of fibers in the oral mucosa and their functions:
Adelta and C fibers: pain Adelta and C fibers: thermal Abeta fibers: touch (?) Adelta fibers: taste
44
relatively fast turnover can ____, but it can also make tissues more vulnerable to conditions that affect ____
speed healing; cell division (like chemo/radiotherapy)
45
"clear" cells (melanocytes and langerhans cells) are dramatically revealed by ____ of _____
lack; cytokeratin staining
46
tyrosinase is an ____ that is the rate-limiting enzyme for controlling the production of ____
oxidase; melanin
47
prickle cell layer appearance due to _____
desmosomes
48
keratinized epithelium can be found on:
gingiva, hard palate, dorsum of the tongue
49
non-keratinized epithelium can be found on:
buccal mucosa, soft palate, alveolar mucosa
50
cytokeratins have a central ____ core, flanked by ____ ends
helical; non-helical
51
cytokeratins assemble into _____ (helical regions critical)
coiled heterodimer
52
? heterodimers = intermediate filament (10 nM)
about 10K
53
strongest cytoskeletal element; resist mechanical force without breaking
intermediate filaments
54
rare autosomal dominant disorder caused by mutations in cytokeratins 4 and 13; affects non-keratinized epithelia; soft, white, spongy plaques that are clinically benign
white sponge nevus
55
cells in the superficial layers of non-keratinized epithelium retain ____ and contain ____
nuclei; cytokeratin tonofilaments
56
cells in the superficial layers of keratinized epithelium contain no ____ but are packed with ____
organelles; cytokeratin (tonofibril)/ fillagrin complexes
57
differences in chemical composition of membrane coating granules creates:
more effective barrier in keratinized epithelium
58
the prickle cell layer of non-keratinized epithelium contains _____, while the prickle cell layer of keratinized epithelium contains _____
tonofilaments; tonofibrils
59
the granular layer of keratinized epithelium contains _____
keratohyalin granules
60
____ is present at the epithelial/ connective tissue interface
basal lamina
61
epithelial/connective tissue interface is convoluted with:
epithelial rete pegs connective tissue papillae (in the papillary layer) reticular layer underneath papillary layer
62
area where lamina propria is connected to muscle, with no submucosa
tongue
63
lamina propria connected to bone, with no submucosa is called a _____
mucoperiosteum
64
areas with mucoperiosteum
gingiva hard palate next to gingiva rugae region median raphe
65
places where there is lining mucosa:
``` alveolar mucosa soft palate underside of the tongue floor of the mouth inside of cheeks ```
66
places with masticatory mucosa
gingiva and hard palate
67
specialized mucosa found on the:
dorsum of the tongue
68
lining mucosa is ____ or ____ epithelium of variable thickness
non-keratinized; parakeratinized
69
presence of submucosa in lining mucosa? | attachment to bone or muscle is ____ and ____
submucosa usually present | attachment to bone or muscle is loose and flexible
70
vascular supply of maxillary gingiva
superior alveolar a. | palatine a.
71
vascular supply of mandibular gingiva
inferior alveolar a. buccal a. mental a. sublingual a.
72
3 ways that vasculature can get into the gingiva
PDL interdental septa oral mucosa

Histo (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions