oral mucosa II, somatosensory and taste Flashcards Preview

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Flashcards in oral mucosa II, somatosensory and taste Deck (39):
1

where does the body of the tongue mucosa come from

BA 1

2

where does the root of the tongue mucosa come from

BA 3

3

is there submucosa in the tongue

no

4

touch sensation

Abeta and Adelta

5

warming

c fibers

6

cooling

Adelta

7

pain

Adelta and c fibers

8

innervation of the anterior tongue

CN V

9

innervation of the posterior tongue

CN IX

10

mechanoreceptor cells include

merkel cells and meissner corpuscles

11

thermo and nociception is detected via

bare nerve endings

12

meissners corpuscles

large axons (Abeta), terminate in the superficial lamina propria b/w rete pegs, complexes of nerve ending encapsulated by schwann cells

13

merkel receptors

lare axons (Abeta), terminate at apices of the rete pegs, complexes of nerve endings and merkel cells

14

merkel cells synapse on

primary afferent neurons

15

merkel ending are

slow adapting...respond both to the changing aspects and static phases of the stiumulus

16

meisnner's ending are

rapidly adapting...respond only to the changing aspects of the stimulus

17

rapid adaptation of the meisnner ending is magnified by

the enfolding schwann cells of the corpuscle that cushion the afferent ending

18

what sensation are meisner or merkel cells able to detect

pain...dynamic range does not extend to the noxious...they have a low threshhold

19

the sensation of spiciness is a part of the

pain system dependent of TRP receptors

20

taste buds are innervated by

CN VII, IX, X

21

fungiform papillae

dorsal ant tongue, BA1, innervated by chorda tympani of VII, monitor food entering mouth, has taste buds, non-k

22

chorda typani of VII is derived from

BA2

23

filiform papillae

heavily keratinized, no buds, innervated by somatosensory fibers (ant tongue...so V)

24

foliate papillae

innervation by IX, lateral posterior tongue, monitor food during chewing, have taste buds (located in the trenches), associated with VE glands

25

circumvallate papillae

c.t core surrounded by trench, posterior tongue, monitor food just before swallowing, innervated by IX, associated with VE glands

26

taste buds in the larynx respond to

deviations from isotonicity to protect the airway

27

there is fn redundancy of the taste buds which make it

resilient to partial taste loss

28

bitter receptors

tas2r, GPC

29

bitter vegetables contain a compound

glucosinolates

30

type I cells of taste buds

dark, express specific proteins, supporting role

31

light cells

have microvilli that reach the taste pore, express receptors for taste substances and respond to taste

32

type II

light type, bitter/sweet/a.a, do not synpase with a primary afferent nerve

33

type III

light type, sour, synapse with primary afferent nerve

34

type II cell synapse

release ATP from a special voltage gated ion channel , CALHM1

35

new taste bud cells differentiate from

basal cells-->precursor that expresses SHH-->all 3 types of bud cells

36

SHH acts on

surrounding cells to maintain taste buds

37

taste bud development

specialization of epithelium into a placode--> cell-cell signalling--> neural innervation--> final differentiation

38

taste buds first appear

EW 8

39

taste pores appear

EW 12