Organ donation and Sourcing Flashcards

1
Q

What is a primary cause of kidney failure?

A

Diabetes (43.8%). HBP (26.8%)

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2
Q

What is the main reason for a heart transplant?

A

Ischaemic heart disease (36%). Idiopathic dilated cardiomyopathy (40%).

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3
Q

What is an altruisitc donation?

A

Donating to a person you do not know personally.

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4
Q

What are paired/pooled donations?

A

Donor and recipient surgery takes place on same day. Pooled is when more than one pair is involved. Can happen when relatives don’t match.

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5
Q

What are 2 types of donation?

A

Living and Cadaveric.

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6
Q

What is made certain before a cadaveric donation takes place?

A

Appropriate testing to ensure brain stem death.

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7
Q

When does a ‘donation after circulating death’ happen? (DCD)

A

Occurs usually after A&E admittance.

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8
Q

Which law lead to the ‘opt out’ system change?

A

Max and Keira’s Law

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9
Q

What percent of UK population supports organ donation?

A

90%

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10
Q

How many UK population provide consent to organ donation in the event of a family members death?

A

68%

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11
Q

Who are the top priority group for transplant allocation?

A

Paediatric patients.

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12
Q

Which 2 organs are given allocation based on ABO match and HLA-match?

A

Kidney and Pancreas.

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13
Q

For kidney and pancreas transplants, which patient types are prioritised?

A

HLA-B, HLA-A, HLA-DR, 000 mismatch.

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14
Q

What factors are considered after paediatric patients?

A

Sensitization (highten’s risk), waiting time, age match and location.

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15
Q

What is cold ischaemic time?

A

Time between ‘chilling’ of organ to transportation and ‘re-activation’.

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16
Q

How many HLA-A mismatches are considered?

A

Only 1.

17
Q

Which HLA-B mismatches are considered?

A

100 and 010.

18
Q

What are the MAIN factors considered for hear an lung transplant allocation?

A

ABO and HLA-DR match. Short CIT is essential. Heart size is also important.

19
Q

What is carried out for heart and lung transplants instead of a crossmatch?

A

A virtual crossmatch is performed.