Organization of the CNS Flashcards

(93 cards)

1
Q

Are exciteable and conductive

A

Neurons

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2
Q

Provide output to muscles, glands (PNS), and other neurons (CNS)

A

Neuron Terminals

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3
Q

Generate action potentials

A

Neuronal Axons

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4
Q

Insulates axons and increases conduction velocity

A

Myelin

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5
Q

The “trigger zone” of the neuron

A

Axon Hillock

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6
Q

Carry sensory information from the periphery

-Associated with receptors

A

PNS Afferents

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7
Q

The cells bodies of PNS afferents are usually in the

A

Dorsal root ganglia

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8
Q

Carry (usually) motor signals to skeletal and smooth muscle

A

PNS Efferents

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9
Q

The cell bodies of PNS efferents are in the

A

Central Nervous System

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10
Q

CNS neurons are mostly

A

Interneurons

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11
Q

Interneurons form connections within the

A

CNS

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12
Q

Connect to neurons in the immediate region

A

Local Interneurons

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13
Q

Project to more distant areas of the CNS

A

Projection interneurons

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14
Q

Receiving areas of neurons can be large or small and vary in dimension. More inputs to a neuron means more

A

Convergence

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15
Q

Number of outputs from axon terminals reflects

A

Divergence

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16
Q

Convergence of information enables integration of

A

Inhibitory and exciteatory information

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17
Q

What are clusters of cell bodies called in the

  1. ) CNS
  2. ) PNS
A
  1. ) Nucleus

2. ) Ganglia

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18
Q

Is mainly cell bodies and synapses

A

Grey matter

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19
Q

Are myelinated axons

A

White matter

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20
Q

Grey and white matter are reversed in the

A

Spinal cord

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21
Q

In the basal ganglia, diencephalon and brainstem, the combined ratio of glial cells to neurons is is

A

11.35

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22
Q

What are the three non-neuronal cells in the CNS?

A

Ependymal, Macroglia, and Microglia

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23
Q

Line the fluid-filled cavities of the brain (ventricles) and the central canal of the spinal cord

A

Ependymal Cells

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24
Q

What are the two types of macroglia?

A

Astrocytes and oligodendrocytes

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25
Phagocytes, active after injury, infection or disease in the CNS -Produce growth factors
Microglia (5-20% of glial population)
26
Form the glial membrane -an important component of Blood-brain barrier
Astrocytes
27
In the blood-brain barrier, control K+ and modulate the vascular tone in the brain, controlling cerebral blood flow
Astrocytes
28
Astrocytes remove K+ from extracellular fluid at nodes of Ranvier during
Action potentials
29
Astrocytes remove neurotransmitters from synaptic clefts, which prevents
Glutamate excitotoxicity
30
Communicate through gliotransmitters(D-serine, glutamate, ATP) in response to adjacent synaptic activity
Astrocytes
31
Produce neurotropic factors and also produce scar tissue in response to CNS injury
Astrocytes
32
Changes in neurons and pathways in response to experience
Neuroplasticity
33
Comprised of the brain and spinal cord
CNS
34
Comprised of the spinal nerves, peripheral nerves, and cranial nerves
PNS
35
Components: 1. Motor efferents to muscle 2. Autonomic efferents to viscera* 3. Sensory afferents from skin, muscle, joints, visceral receptors
Spinal nerves
36
Sends motor efferents to muscle and autonomic efferents to viscera
Spinal nerves
37
In the thoracic and upper lumbar regions, spinal nerves are
Sympathetic
38
In the sacral region, spinal nerves are
Parasympathetic
39
Form peripheral nerves made up of connective tissue and fascicles with afferents and efferents
Spinal Nerves
40
Fluid filled cavities in every region of the central nervous system Cerebrospinal Fluid (CSF)
Ventricles
41
The spinal cord extends from the
Foramen magnum to the L1 vertebral body
42
Has white matter pathways
Spinal cord
43
For the long tracts, the sensory pathways are made up of
3 Neurons
44
Spinal cord lesions that interrupt motor pathways can cause
Paralysis
45
What are the two types of spinal cord reflex circuits?
1. ) Simple (monosynaptic): Stretch reflex | 2. ) Complex (multiple synapses): Flexor withdrawal reflex
46
The "little brain" dorsal to the brainstem
Cerebellum
47
The cerebellum functions in
Movement and balance
48
Damage to the cerebellum causes
Ataxia (Disordered movement)
49
What are the three parts of the brainstem?
1. ) Medulla 2. ) Pons 3. ) Midbrain
50
Most of the cranial nerves exit on the
Ventral surface of brainstem
51
The ventral surface of the brainstem contains the
Cerebral peduncles and pyramid
52
The cerebral peduncle is located in the
Midbrain
53
The pyramid is located in the
Medulla
54
The transition between the spinal cord and brainstem
Medulla
55
Which 4 cranial nerves are part of the medulla?
IX, X, XI, and XII
56
Responsible for the regulation of body homeostasis, such as HR, respiration, vasomotor tone, and gastric secretions
Nuclei of the medulla
57
Damage to the medulla =
Death
58
Vomiting, coughing, sneezing, swallowing, and gagging are reflexes related to the
Medulla
59
Which 4 cranial nerves are part of the pons?
V, VI, VII, and VIII
60
The pons is responsible for
Balance, sound localization, eye movement, and coordination
61
Is a large pathway into the cerebellum
Pons
62
Located at the top of the brainstem
Midbrain (mesencephalon)
63
Which 2 cranial nerves are part of the midbrain?
CN III and IV
64
The nuclei of the midbrain are responsible for
Visual reflexes and motor control
65
Has dopamine projections to the cortical areas of the cortex
Midbrain
66
These dopamine projections are significant for
Movement and "reward"
67
Has a net-like appearance and passes through the core of the brianstem
Reticular formation
68
The reticular formation includes projections to the
Cortex or spinal cord
69
Rostral projections from the pons and midbrain (pontomesencephalic)
Reticular activating system
70
The reticular activating system projections controls
Attention, arousal, sleep, and wakefulness
71
Can lead to loss of consciousness and Coma
Lesions of the reticular formation
72
Major relay station for all inputs to the cortex -examples: sensory (except olfactory), motor areas
Thalamus
73
Projections to the cortex are called
Thalmocortical radiations
74
The diencephalon is made up of the
Thalamus, hypothalamus, epithalamus, and subthalamus
75
The cerebral hemisphere is called the
Telencephalon
76
The elevations in the cerebral hemisphere
Gyri
77
The depressions in the cerebral hemisphere
Sulci
78
The deepest depressions are called
Fissures
79
What are the two major sulci?
Sylvian fissure and Central sulcus
80
What are the 5 lobes of the brain?
Frontal, Parietal, occipital, temporal, and limbic
81
Responsible fro planning, organizing, and controlling behavior
Frontal lobe
82
Responsible for Sensory perception of self and the world
Parietal lobe
83
The occipital lobe is responsible for
Visual processing
84
Responsible for auditory (superior), visual (middle) and memory (medial) processing
Temporal lobe
85
Responsible for emotional processing and memory consolidation
Limbic lobe
86
The first cortical receiving area for sensory information
Primary sensory cortex
87
The last cortical area to project to the spinal cord and brainstem -Right controls/perceives left; left controls/perceives right
Primary motor cortex
88
The primary cortex is divided into primary sensory and primary motor cortex by the
Central sulcus
89
Sensory “fields” are represented in an orderly manner within the
Primary cortex
90
Responsible for higher-order processing, e.g. perceptions, judgments, organization, calculations, language
Association Cortex
91
Responsible for emotion and memory
Limbic System
92
Part of the limbic system that is important for long-term memory formation
Hippocampus
93
The part of the limbic system that is important for Fear-learning
Amygdala