Orofacial Granulomatosis

Question 1

What is angio-oedema?

Answer 1

oedema of the oral and facial soft tissues due to an INCREASE in fluid exudate from the capillaries but with no lymphatic drainage

Question 2

what is orofacial granulomatosis?

Answer 2

clinical presentation of oedema in the oral and facial soft tissues by blockage of lymphatic drainage due to an immune reaction

Question 3

What is the difference between angio-oedema vs OFG?

Answer 3

• angio-oedema swelling comes up quickly & settles quickly (24-48 hours)
• OFG swelling comes up quickly & settles very slowly (over weeks or months)

Question 4

During the exclusion diet trial, what foods should be avoided?

Answer 4

All foods containing =
- benzoic acid
- scorbic acid
- cinnamon products
- chocolate

Question 5

What intralesional steroid injection is injected into areas of swelling in OFG patients?

Answer 5

Triamcinoclone

Question 6

What systemic treatment is used to help immune modulation in OFG patients?

Answer 6

• Pulsed azithromycin for 3 months - 3 days in every week
• prednisolone for short term issues