Orthopedics/Rheumatology High Yield Flashcards Preview

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Flashcards in Orthopedics/Rheumatology High Yield Deck (25):
1

What is Gout

Uric Acid Deposition in soft tissue, joints, bones

2

What is a common cause of Gout

Purine rich foods like alcohol, liver, oily fish, yeast

3

Sx of Gout

Podagra: 1st MTP joint is red and painful
Tophi Deposition: Collection of solid uric acid in soft tissue

4

Dx of Gout

Arthrocentesis: Negative Bifringent Needle Shape Urate Crystals
Xrays: Rat Bite, Punched out Erosions

5

Tx of Gout

NSAIDS (indomethacin)
Colchicine 2nd line
For chronic: Allopurinol

6

What is Pseudogout

Calcium Pyrophosphate deposition in joints
Knee is red, swollen and tender
See Cartilage Calcifications (Chondrocalcinosis)

7

Dx of Pseudogout

Arthrocentesis: Positively birefringenet, Rhomboid Shaped CPP Crystals

8

Tx of Pseudogout

Corticosteroids are 1st line
NSAIDS
Colchicine for prophylaxis

9

What is Sjogren's Syndrome

Autoimmune disorder attacking exocring glands

10

Sx of Sjogren's Syndrome

Salivary: Xerostoma (dry mouth)
Lacrimal: Keratoconjunctivitis sicca (dry eyes)
Parotid Enlargement

11

Dx of Sjogren's Syndrome

ANA
AntiSS-A
AntiSS-B
Positive RF
Shirmer Test (decreased tear production)
Biopsy of gland

12

Tx of Sjogren's Syndrome

Artificial Tears, Pilocarpine
Cevimeline stimulates muscarinic cholinergic receptors

13

What is Polymyositis

Idiopathic inflammatory muscle disease of proximal limbs, neck, pharynx

14

Sx of Polymyositis

Progressive symmetrical proximal muscle weakness (not painful)
Dysphagia, Skin Rash, Polyarthrlagias, Muscle Atrophy (difficulty combing hair, climbing stairs)

15

Dx of Polymyositis

Aldolase
Anti-SRP antibody
Muscle Biopsy: See inflammation around the individual muscle fiber (endomysial involvement)

16

Tx of Polymyositis

High dose steroids
Methotrexate

17

What is Reactive Arthritis (Reiter's Syndrome)

Autoimmune response to infection

18

Sx of Reactive Arthritis

Can't see, can't pee, can't climb a tree
Conjunctivitis/Uveitis, Urethritis, Asymmetric inflammatory arthritis
Sausage toes/fingers

19

What infections preceded Reactive Arthritis

Chlamydia, Gonoarrhea, GI (Salmonella, Shigella)

20

Dx of Reactive Arthritis

HLA-B27
Synovial Flud WBC will be

21

Tx of Reactive Arthritis

NSAIDS

22

What is Scleroderma

Systemic connective tissue disorder
Thickened skin, lung, heart, kidney, GI tract

23

Sx of Scleroderma

Tight, Shiny, Thickened skin due to fibrous collagen buildup
CREST syndrome
Calcinosis cutis, Raynaud's Phenomenon, Esophageal MOtility disorder, Sclerodactyly, Telangectasis
Pulmonary HTN

24

Dx of Scleroderma

Anti-Centromere AB
Anti-SCL-70 antibodies
Positive-ANA

25

Tx of Scleroderma

DMARDS, Steroids
Vasodilators for Raynaud's: CCB, Prostacyclin