ORUC ET AL (1997) RESULTS/CONCLUSIONS

Question 1

Can you summarise the main result of the study?

Answer 1

Ppts with bipolar and a family history of mood disorders where NOT more likely to have polymorphisism/ variations in the investigated genes ~thus there is no significant association between variations in these genes and bipolar.

Question 2

Can you summarise the gender related results of the study?

Answer 2

• Serotonin is sexually dimorphic- behaves differently in men and women.
• Females with bipolar disorder were more likely to have variations in these serotonin receptor genes (suggesting a potential genetic risk for bipolar in females with these genetic variatiosn)