Average osmolarity of ICF and ECF in human body.
290 mOsm, can range from 270 - 300 mOsm
What is Normal saline?
0.9% of sodium chloride which is isosmotic to red blood cells?
You need to memorize the estimated osmalility equation.
What is it?
Estimated Osmolality = (2x [Na]) + ([glucose]/18) + ([BUN}/2.8)
BUN = Blood urea nitrogen
Fancy term for shrinking of RBC due to hyperosmotic gradient.
What cells do not function well in osmalarity changes?
Neurons, some thirst ones respond better, and overall many cells in the body will not respond well.
Reflection Coefficient closer to 1?
Closer to 0?
1 = Tonocity and Osmolarity match
0 = Will not match , solute in question does not provide osmotic pressure
Hypotonic solutions cause what to happen to a cell?
Hypotonic - water moves in
Hypertonic- water movesout